5. Jiang, D., Kong, N.C., Gu, X., Li, Z., and He, Y. (2011). Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant development. PLoS Genet 7, e1001330. 10.1371/journal.pgen.1001330. 编辑︱杨彬薇 本文完 http://weixin....
求翻译:COMPASS-like complexes containing MLL1 or MLL2 include the unique subunit menin (FIG. 1b), which can act as a tumour suppressor 22 and is required for localization of the complex to chromatin 23. MLL1 is required for H3K4 trimethylation at a small subset of mammalian ...
In animals, several mechanisms have been described as to how COMPASS complexes are guided to the correct genomic loci, involving either proteins that recognize DNA elements, or non-coding RNA. For plants, it remains unknown as to how the COMPASS-like complex is recruited to targets on the DNA...
Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. Mol Cell Biol. 2013; 33:1698-1701. [PubMed: 23459940]Morgan MA, Shilatifard A. Drosophila SETs its Sights on Cancer: Trr/MLL3/4 COMPASS-like complexes in Development and Disease. Molecular ...
(HAT).bSchematic of KCDCOM. COMPASS-like complexes (KCDCOMs, also historically known as ASC2-binding complexes, ASCOMs) bind multiple unique subunits (NCOA6/ASC2, KDM6A/UTX, PTIP, and PAGR1/PA1) and interact with chromatin via histone tail post-translational modifications and DNA binding ...
Histone H3 lysine 4 (H3K4) methylation is catalyzed by the highly evolutionarily conserved multiprotein complex known as Set1/COMPASS or MLL/COMPASS-like complexes from yeast to human, respectively. Here we have reconstituted fully functional yeast Set1/COMPASS and human MLL/COMPASS-like complex in...
Benoit Thuilot, Bernard Espiau Th eme 4 | Simulation et optimisation de syst emes complexes Projet BIP Rapport de recherche n2996 | October 1996 | 86 pages Abstract: It is well-known that a suitably designed unpowered mechanical biped robot can walk" down an inclined plane with a steady...
first things that come to mind may be the majestic temples sprinkled about the city – glistening golden under the radiant sun, the wild nightlife of the city centre that never sleeps or the string of shopping complexes and local shops that offer fashion merchandise at a different price range...
Because the Swd1 and Set1 residues constructing the Kabuki pocket are highly conserved from yeast to humans, the inter-subunit pocket is expected to exist in all yeast and animal COMPASS and COMPASS-like complexes and potentially serves as a common regulatory site (Figure S3). Minimally, the ...
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