No person is born with a choice of genes. Alterations in DNA can result from a mutation in a single gene, chromosome abnormalities, or multi-factorial disorders. When genetic disorders do occur, they are often rare, and affect one person among thousands of individuals. ...
Mitochondrial inheritance Most genetic diseases are the direct result of a mutation in one gene. However, one of the most difficult problems ahead is to further elucidate how genes contribute to diseases that have a complex pattern of inheritance, such as in the cases of diabetes, asthma, cancer...
20 Inflammatory bowel diseases 302 Jean-Pierre Hugot 21 Genetic anemias 316 W. G. Wood and D....
Scientists discover genetic secrets of seven common diseasesWILLIAM TINNING
Background Studies examining whether genetic risk information about common, complex diseases can motivate individuals to improve health behaviors and advan... KD Christensen,JS Roberts,BJ Zikmund-Fisher,... - 《Genome Medicine》 被引量: 8发表: 2015年 Are There Modifiable Risk Factors to Improve AK...
LD maps have some of the useful properties of genetic linkage maps but have a much higher resolution which is optimal for SNP-based association mapping of common diseases. The studies that have been undertaken to date suggest that LD and recombination maps show some close similarities because of...
et al. An atlas of genetic correlations across human diseases and traits. Nat. Genet. 47, 1236–1241 (2015). CAS PubMed PubMed Central Google Scholar Okbay, A. et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide...
Age is a common risk factor in many diseases, but the molecular basis for this relationship is elusive. In this study we identified four disease clusters from 116 diseases in UK Biobank data, defined by their age-of-onset profiles, and found that diseases with the same onset profile are ge...
Find all the latest on common diseases at Medical Xpress. Your go-to source for news, research, and medical breakthroughs.
While extensive research has been done since 1993, when the genetic cause of the disease was discovered [1], there is still no cure for this disease nor an effective treatment. Clinical and imaging biomarkers have been developed that measure the disease state and progression [2]. Nevertheless,...