coli (Algorithm 1; ICD-10-CM:A41.51; base case) as well as a broader, previously validated, claims-based algorithm for infectious invasive disease/organ dysfunction with concomitant E. coli infection (Algorithm 2; sensitivity analysis) [43]. Each of the algorithms is described in greater ...
coli sepsis (ICD-10-CM code A41.51); odds ratios (OR) were estimated using weighted logistic regression. Sensitivity analyses within 90 days and using broader claims-based algorithm for IED were conducted.Figure 1.IED rates 30 days post index by IED case-identification algorithm RESULTS. Overall...
coli MKS111ΔHBB MG1655 ΔfimA-H ΔfliCD ΔflgM ΔfliFGH ΔflgDEFGHIJ This study E. coli DH10B endA- RecA- Dam/Dcm+ [66] Plasmids pMCS3'UTR Multiple cloning site preceding the 3'UTR sequence of fliC in PvuI-EcoRI of pBR322 [21] pPeb15'3' pLA25 pLA26 173 bp fliC promoter ...
Bush, L.M., MD and Perez, M.T., MD. (Reviewed 2016 May). Escherichia coli infections. Merck Manual Professional Version. Available online at https://www.merckmanuals.com/professional/SearchResults?query=Escherichia+coli+++Infections&icd9=041.4%3b008.0%3b038.42%3b482.82. Accessed 7/17/2016....
(iii) changing the start codon oficd(encoding isocitrate dehydrogenase) from ATG to GTG to balance cell growth and lysine production4(Fig.1a). After fed-batch fermentation using the defined medium AM1,E. coliLys1 exhibited a 50.4% increase in lysine titer, a 30.3% increase in yield, and ...
One potential mechanism for such a regulation has already been described: phosphorylation of isocitrate dehydrogenase (icd) in E. coli occurs at Ser113, the residue involved in binding of the substrate (isocitrate), and therefore abolishes the enzyme action (37). Another such example may come ...
The following housekeeping gene fragments were assessed: adk (adenylate kinase), fumC (fumarate hydratase), gyrB (DNA gyrase), mdh (malate dehydrogenase), purA (adenylate succinate dehydrogenase), icd (isocitrate/isopropylmalate dehydrogenase), and recA (ATP/GTP-binding motif). Each unique sequence ...
ST designation was determined using MLST v.2.19.0 (https://github.com/tseemann/mlst) based on allelic variation in seven single copy housekeeping genes (adk, fumC, gyrB, icd, mdh, purA, recA; [18]) and compared against previously characterized STs in theE. colidatabase in PubMLST [44]...
The NADPH production value was sum of fluxes of the gdh, gnd and icd steps, while the NADH production value should be sum of fluxes of the eno, pdh, akd, mdh and mez steps. However, the fluxes associated with the pox step and the pdh step cannot be separated in our model. This is...
Patient comorbidities and invasive procedures were transcribed with Canadian ICD-10 codes. See Appendix 1 for clinical definitions. Bacterial isolates, identification and susceptibility testing All E. coli isolates from blood were routinely stored at Calgary Laboratory Services and were available for this ...