人类同源基因 COL1A1 品系描述 通过敲除Col1a1基因exon 2-5,建立Col1a1基因敲除小鼠模型。 *使用本品系发表的文献需注明: Col1a1-KO mice (Cat. NO. NM-KO-226315) were purchased from Shanghai Model Organisms Center, Inc.. 你也可能感兴趣
图1.The H11 genomic locus in cytoband A1 (~3 cM) between Eif4enif1 and Drg1 genes. 和Rosa26位点的过表达模型一样,在H11位点我们也可以采用CRISPR/Cas9技术构建条件性基因过表达小鼠模型,即广泛型强启动子pCAG与外源目的基因cDNA之间用loxP-STOP-loxP结构隔开,只有与组织特异性Cre工具鼠交配后,才会在特异...
To understand the roles of Wnt/β-catenin signaling in the dento-alveolar complex formation, we generated conditional β-catenin activation mice through intercross ofCatnb+/lox(ex3)mice withCol1a1-cremice. In mutant mice, tooth formation and eruption was disturbed. Lower incisors and molars did ...
Col1a1(3.6)-Cre-mediated deletion of Pkd1 results in osteopenia in Col1a1(3.6)-Cre;Pkd1flox/null newborn mice.Ni, QiuZhousheng, XiaoLi, CaoValentin, DavidLeigh, Darryl Quarles
These include (1) expression of platelet derived growth factor receptor-β (PDGFrβ), but not the pericyte marker desmin and (2) they are labeled in GLAST-CreErt [11] and Collagen1a1-GFP (Col1a1-GFP) [48] transgenic mouse lines. It is not clear, however, if the cells labeled by ...
Angpt1+ mice had a lower percentage of circulating B cells and a higher percentage of myeloid cells than Col1a1-Cre-/COMP-Angpt1l+ (control) mice... YM Ikushima,F Arai,Y Nakamura,... - 《Biochem Biophys Res Commun》 被引量: 18发表: 2013年 Wound healing genes and susceptibility to...
25 Forlino A, Porter FD, Lee EJ, Westphal H, Marini JC: Use of the Cre/lox recombination system to develop a non-lethal knock-in murine model for osteogenesis imperfecta with an alpha1(I) G349C substitution. Variability in phenotype in BrtlIV mice. J Biol Chem 1999; 274: 37923–3793...
Transgenic Mice Expressing a Ligand-Inducible Cre Recombinase in Osteoblasts and Odontoblasts : A New Tool to Examine Physiology and Disease of Postnatal B... To develop a usable tool for such study, we generated transgenic mice in which a 2.3-kb mouse Col1a1 proximal promoter, which is activ...
These include (1) expression of platelet derived growth factor receptor-β (PDGFrβ), but not the pericyte marker desmin and (2) they are labeled in GLAST-CreErt [11] and Collagen1a1-GFP (Col1a1-GFP) [48] transgenic mouse lines. It is not clear, however, if the cells labeled by ...
将IRES-CreERT2插入到小鼠Col1a1基因终止密码子处。CreERT2有泄露情况,请根据研究目的使用该品系。 应用领域:Cre工具鼠,成骨细胞 *使用本品系发表的文献需注明: Col1a1-IRES-CreERT2 mice (Cat. NO. NM-KI-225031) were purchased from Shanghai Model Organisms Center, Inc.. ...