Codon change statistics for GMV start site changes in medium and high diversity genome test sets.Michael, E. WallSindhu, RaghavanJudith, D. CohnJohn, Dunbar
(57) How to recombine a library of nucleic acid that has been [summary] codon change is provided. The nucleic acid, as compared to the wild type sequence, in addition to codon changes and modifications may include non-conservative or conservative modifications of the coding sequence. Also a ...
One-step high-efficiency CRISPR/Cas9-mediated genome editing in Streptomyces The RNA-guided DNA editing technology CRISPRs (clustered regularly interspaced short palindromic repeats)/Cas9 had been used to introduce double-stranded b... H He,G Zheng,W Jiang,... - 《生物化学与生物物理学报(英文)...
Silent Mutation: No codons are changed so as to alter the polypeptide sequence of the protein product of a gene. Missense Mutation: At least one codon is altered so as to change its coded amino acid, thus altering ...
In the present study, by using the minor form of brazzein as the basic sequence, the codon-optimized brazzein gene was designed based on appropriate GC content and preferred codon of E. coli . Then, the synthesized brazzein gene was cloned in pET28a vector and expressed in BL21(DE3) and...
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Heterozygosity for the IVS-I-5(G→C) mutation with a G→A change at codon 18 (Val→Met; Hb Baden) in cis and a T→G mutation at codon 126 (Val→Gly; Hb Djonburi) in trans resulting in a thalassemia intermedia 来自 Elsevier 喜欢 0 阅读量: 46 作者: Vladimir Divoky and ...
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(57) How to recombine a library of nucleic acid that has been [summary] codon change is provided. The nucleic acid, as compared to the wild type sequence, in addition to codon changes and modifications may include non-conservative or conservative modifications of the coding sequence. Also a ...
Fingerprinting and amino acid analysis of the tryptic peptides from the two chain types have shown that they differ by a single amino acid substitution, between lysine and aspartic acid, which requires a two-nucleotide change in the corresponding codon. Another substitution in the same codon is ...