Synonymous Codon Changesdoi:10.1007/3-540-29623-9_8865Nucleobase(s) of a coding triplet are changed in such a way that – due to the degenerated code – the triplet still encodes the same amino acid. SNP Detection and Mass Spectrometry...
Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture. Retrovirology. 2013;10:78.Martrus, G., Nevot, M., Andres, C., Clotet, B., Martinez, M.A.: Changes in codon-pair bias of human immunodeficiency virus type 1 ...
While direct studies linking mechanical stretch to PEPCK in cancer are limited, the connection seems plausible. Mechanical stretch can induce inflammation and metabolic changes, and in cancer, this could upregulate PEPCK, supporting a cell state that aligns with prolonged survival and disease promotion...
Share on Facebook nonsense mutation (redirected fromCodon, nonsense) Medical nonsense mutation [′nän‚səns myü‚tā·shən] (cell and molecular biology) A mutation that changes a codon that codes for one amino acid into a codon that does not specify any amino acid (a nonsense ...
Decoding mechanisms by which silent codon changes influence protein biogenesis and function 9Concluding remarks Studies during the past 15 years have demonstrated thatcodon usageplays a crucial role regulating cellular function, and have led to a general understanding of the mechanisms by which these eve...
One-step high-efficiency CRISPR/Cas9-mediated genome editing in Streptomyces The RNA-guided DNA editing technology CRISPRs (clustered regularly interspaced short palindromic repeats)/Cas9 had been used to introduce double-stranded b... H He,G Zheng,W Jiang,... - 《生物化学与生物物理学报(英文)...
Missense mutation --- A mutation that changes a codon specific for one amino acid to specify another amino acid. 突变成编码另一种氨基酸的密码子。 This change, which creates a stop codon at codon 28 of the pre core (PC) protein, causes premature termination of the PC protein. 这个转变在...
Quantifying the impact of changes in effective population size and expression level on the rate of coding sequence evolution population-genetics scientific-publications codon-models Updated on Mar 22 HTML alondmnt / codon-bias Star 0 Code Issues Pull requests Python package of codon usage bias ...
The gene expression signature in cancer is often significantly altered, and this is often by elevated activity of oncogenic transcription factors [1,2]. However, changes at the level of transcription do not always directly reflect the change in protein level; [3] post-transcriptional regulation is...
6c). Meanwhile, 1×UGA fluorescence fold changes were similar across all strains, resulting from increased fluorescence in the absence of nsAAs (Extended Data Fig. 9d). This effect probably resulted from previously observed mischarging of Mj-tRNA by pAzRS.2.t113. Overall, these data reveal ...