解析 正确 有意义链(Sense strand)是指与mRNA序列相同的DNA链。在DNA双链中,携带遗传信息并直接用于转录的链称为模板链(非编码链),而与之互补的另一条链即为编码链(有意义链)。mRNA的合成基于模板链的碱基互补配对,因此其序列与有意义链一致(仅以U代替T)。题目描述符合该定义,表述完整无误。反馈 收藏
The sequence of bases in the mRNA transcribed from strand A of DNA written 5′- to 3′- is V. UCGAGUAGCCGAUGAUCAUCGUCGACGA The amino acid sequence coded by the above mRNA is VI. Ser-Ser-Ser-Arg-STOP However, if DNA strand B is the coding strand the mRNA sequence will be: VII. ...
使用编码双链启动子一条链的引物的方法 The coding strand of a double-stranded promoter primer methoddoi:CN102268428 A本发明提供了通过使用编码双链启动子一条链的启动子引物获得环形单链DNA转录底物而由RNA聚合酶来制备对应于靶序列的转录产物的方法,组合物和试剂盒. The present invention provides a promoter...
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The strand attaches to Argonaute 2 (AGO2), which is the major protein of the RNA-induced silencing complex (RISC). miRNAs are included in the RISC. They can regulate gene expression in a posttranscriptional manner through formation of miRNA response elements (MREs) by binding to specific ...
Figure 3. Disruption of the miR-183-Binding Site in the Coding Region of βTrCP1 mRNA Stabilizes It and Induces βTrCP1 Expression and Activity (A) Predictions of hybrids of βTrCP1 and βTrCP2 mRNAs (lower strand) with the corresponding miRNA (upper strand) were performed using RNAhybrid...
and intergenic. Intergenic and enhancer-associated lncRNAs have distinct promoters and are independent of protein-coding genes. Conversely, bidirectional lncRNAs share a common promoter but are transcribed from the opposite strand of a protein-coding gene. Intronic lncRNAs originate within the introns of...
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What may also occur is loading of the passenger strand instead of the guide strand into RISC, and toxicity, especially connected to cell proliferation [168,171]. Effective and safe delivery is another critical issue. By nature, oligonucleotides are hydrophilic and negatively charged which poses a ...