What is myelin? What type of cells makes myelin in the PNS and in the CNS? What are the main parts of Peripheral Nervous System (PNS)? What are the main parts of central nervous system? A collection of neuron cell bodies outside of the CNS is called a ___. ...
Mesenchymal stem cells (MSCs) are adult bone marrow-derived stem cells actually proposed indifferently for the therapy of neurological diseases of both the Central (CNS) and the Peripheral Nervous System (PNS), as a panacea able to treat so many different diseases by their immunomodulatory ability...
Background: The extracellular matrix of the PNS/CNS is unusual in that it is dominated by glycosaminoglycans, especially hyaluronan, whose space filling and hydrating properties make essential contributions to the functional properties of this tissue. Hyaluronan has a relatively simple structure but its...
The main glial cells of the PNS and CNS can be identified both in situ and in culture by the use of combinations of different antibodies which act as markers for the different cell types. The particular combination of antibodies chosen depends very much on the developmental stage and anatomical...
Central Nervous System (CNS) Brain Spinal Cord Peripheral Nervous System (PNS) Sensory Neurons Motor Neurons Somatic Nervous System voluntary movements via skeletal muscles Somatic Nervous System voluntary movements via skeletal muscles Autonomic Nervous System organs, smooth muscles Autonomic Nervous System ...
For example, vesicular stomatitis virus envelope G-protein (VSV-G) -pseudo-typed virions feature more efficient cell entry and transduction of a variety of mammalian cells11. BacMam is a genetically engineered baculovirus with VSV-G-modified capsid protein that contains a DNA cassette for ...
Prerequisites for functional recovery following axonal interruption (i.e. axotomy) in the central (CNS) or peripheral nervous system (PNS) are: 1) Survival of the injured neuron; 2) Axon regrowth of sufficient length to reach its target; 3) Axon guidance
p vs 32wt * ** *** NS NS NS NS CNS + PNS CNS + PNS CNS + PNS PNS only PNS only PNS only PNS only *** Table 2. Summary of coupling between pairs of cells expressing the indicated mutants, WT Cx32 or vector-EGFP in the homotypic configuration....
Neuronal progenitor cells Nrf2: Nuclear factor erythroid 2-related factor 2 NMJs: Neuromuscular junctions NO: Nitric oxide NS: Non-structural protein ORF: Open reading frame PAMPs: Pathogen-associated molecular patterns PNS: Peripheral nervous system ...
(VAMP1/2/3) to prevent vesicle fusion with the plasma membrane (i.e., exocytosis) and has no other known targets29,30(Fig.1b). We crossed iBot andCnp-Cre mice to conditionally inactivate VAMP2/3 in pre-myelinating cells of the CNS and PNS31, hereafter referred to as iBot;Cnp-Cre...