The data analyzed, included maternal date of birth, age, gravidity- and parity-status, CMV serostatus (IgG positive/ IgM negative—seropositive patients, IgG negative/ IgM negative—seronegative patients and IgG positive/ IgM positive and low IgG avidity—patients with a primary infection), due ...
IgG antibodies indicate past infection and immunity, while a rise in IgM suggests recent or active reactivation [99,100]. CD163+ macrophages, CD68+ macrophages, and CD3+ T-cell infiltrates are located in juxtaposition to CMV-positive cells during persistent ocular CMV infection [101]. Further...
HCMV-seropositive individuals comprise 89.83% of CVD patients, 69% of SMI patients, and 70.37% of COVID-19 patients. No differences in HCMV seroprevalence or HCMV IgG antibody titres were observed between patients and HDs. A significant reduction in Spanish HCMV seroprevalence among HDs was ...
Among 114 healthy blood donors, 80% were HCMV-IgG positive. HCMV specific IgG levels were significantly higher in brain tumor patients compared to corresponding age-matched healthy blood donors. Although this patient cohort represents a small sample size, the HCMV-specific IgG prevalence observed ...