What is clozapine, and how does it work (mechanism of action)? Clozapine is an anti-psychotic medication that works by blocking receptors in the brain for several neurotransmitters (chemicals that nerves use to communicate with each other) including dopamine type 4 receptors, serotonin type 2 ...
an increased risk of death.[1][8] Common side effects include drowsiness, decreased or increased saliva production, low blood pressure, blurred vision, and dizziness.[1] The potentially permanent movement disorder tardive dyskinesiaoccurs in about 5% of people.[8] Its mechanism of action is not...
How does clozapine work (mechanism of action)? Clozapine belongs to a group of medicines called second-generation (atypical)antipsychotics. It is thought to work by balancing brain chemicals called serotonin and dopamine. These chemicals are known to affect thoughts and mood. Clozapine also acts on...
10.2 Management of Overdosage 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.2 Pharmacodynamics 12.3 Pharmacokinetics 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility 14 CLINICAL STUDIES 14.1 Treatment Resistant Schizophrenia ...
(<) 500/μL, occurs in a small percentage of patients taking CLOZARIL and is associated with an increase in the risk of serious and potentially fatal infections. Risk of neutropenia appears greatest during the first 18 weeks on treatment and then declines. The mechanism by which CLOZARIL ...