treatment-resistant schizophreniaaffective disordersBrief Psychiatric Rating Scale, Expanded Versionbipolar featuresEvidence indicates that is effective in the management of and in . To examine whether affective components within the boundaries of the spectrum imply specific psychopathological characteristics of ...
In treatment-resistant schizophrenia, clozapine is considered the gold standard worldwide. Due to safety concerns (agranulocytosis, clozapine myocarditis) and poor tolerance (e.g., epileptic seizures, salivation, weight gain, sedation) it is rarely and almost always prescribed only many years after...
One fifth to one third of people suffering from schizophrenia is considered as treatment resistant. In other words, these people have persistent psychotic symptoms and poor functioning despite adequate treatment with conventional or novel antipsychotics.To date one of the most effective medications is ...
Clozapine, a poorly tolerated antipsychotic drug, is widely recognized as the only efficacious option in treatment-resistant psychosis. The United Kingdom (U.K.) National Institute of Clinical Excellence (NICE) guidance for its consideration defined a threshold for treatment resistance substantially more...
Of the total sample, 609 patients (62%) were diagnosed as having schizophrenia and 371 (38%) as having schizoaffective disorder. At the time of enrollment, 263 patients (27%) were rated as treatment resistant. Of the total population studied, 477 patients received olanzapine, 479 received ...
Reduces suicidal behavior even as first-line therapy in patients with non-treatment-resistant schizophrenia andschizoaffective disorder. Improves cognition and thereby, quality of life in patients with schizophrenia. Decreases the incidence of schizophrenia relapse. ...
However, approximately % 30 of the patients is treatment-resistant. Clozapine is a new agent for treatment-resistant schizophrenia. The aim of this study was to examine the efficacy of clozapine in treatment-resistant schizophrenia. Fourty seven treatment-resistant schizophrenic patients who admitted to...
Treatment-resistant schizophrenia is the object of intense interest because of recent developments in its treatment and aetiology. The actual definition of... H Y,Meltzer - 《Current Medical Research & Opinion》 被引量: 358发表: 1997年 Treatment of Clozapine-induced Obsessive-compulsive Symptoms in...
Cook B, Hoogenboom G (2004) Combined use of amisulpride and clozapine for patients with treatment-resistant schizophrenia. Australas Psychiatry 12:74–76Cook B, Hoogenboom G. Combined use of amisulpride and clozapine for patients with treatment-resistant schizophrenia. Australas Psychiatry 2004 Mar; 12...
BACKGROUND: The aim of this study was to evaluate the long-term efficacy and safety of clozapine in patients with treatment-resistant schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic features. METHOD: 101 patients with a DSM-III-R diagnosis of schizophrenia (N = 34);...