Aim: To describe the Clozapine white blood cell monitoring practice and outcomes in a local psychiatric hospital. Setting: At a specialist Psychiatry unit in Durban, KwaZulu-Natal, which follows a modified algorithm of the South African Standard Treatment Guidelines ...
Clozapine treatment remains the gold standard for treatment-resistant schizophrenia. This study aimed to describe temporal trends in clozapine use at discharge among patients with schizophrenia at two of the largest public psychiatric hospitals in Taiwan
Its unfavourable side effect profile and the need for ongoing blood monitoring do not make it a popular choice in planning treatment with young people with first-episode psychosis (FEP) and may lead to a delay in its use. In the UK, the National Institute of Clinical Excellence (...
Therefore, they would be an ideal HCP to lead a team approach to enhance patient monitoring, treatment, and improved guidelines to prevent clozapine induce hypomotility. Pharmacogenomic testing for specific genes associated with the pharmacodynamic action, metabolism or clearance of antipsychotics may ...
Regular blood monitoring is required for the prescription of clozapine in many countries. Other adverse effects include hypersalivation, metabolic disturbances including weight gain and diabetes, sedation, seizures, and constipation [8]. Constipation is difficult, incomplete, or infrequent evacuation of ...