Clozapine belongs to a class of drugs known as atypical antipsychotics. Serum concentration of CLZ is associated with clinical response and dose-dependents side effects, where generalized tonic-clonic seizures are most critical. Thus, therapeutic drug monitoring (TDM) of CLZ may guide individual ...
Clozapine belongs to a class of drugs known as atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. How to use Clozapine ODT If you are using the liquid form of this medication, read the Patient Information Leaflet if available from ...
What other drugs will affect clozapine?When you start or stop taking clozapine, your doctor may need to adjust the doses of any other medicines you take on a regular basis.Clozapine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for ...
Drug class: Atypical Antipsychotics VA class: CN709 Chemical name: 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4] diazepine CAS number: 5786-21-0Medically reviewed by Drugs.com on Nov 19, 2024. Written by ASHP.Introduction Uses Dosage Warnings Interactions Stability Warning...
Related Drugs Fazaclo User Reviews Drug Summary What Is FazaClo? FazaClo (clozapine) is an antipsychotic medication used to treat severe schizophrenia symptoms in people who have not responded to other medications. FazaClo is also used to help reduce the risk of suicidal behavior in people with...
Forty-three reports involving 19 different drugs were evaluated. Clozapine appeared to be involved in pharmacokinetic and pharmacodynamic interactions when prescribed concurrently with most major classes of therapeutic agents. In general, the addition of other medications with similar pharmacological effec...
and the estimated 20 to 40% of patients who develop tardive dyskinesia on long term therapy. Clinical options for the management of treatment-resistant schizophrenia are limited: common clinical practice is to increase the existing antipsychotic dose or to switch to a different class of antipsychotic...
Clozapine is known to treat both positive and negative symptons, and unlike many other psychoactive drugs, can actually increase a patient's clarity of thought and perception of reality. There are other uses for this drug, but they are considered "off-label" or in the experimental or testing ...
20.The company enjoyed some successes in the field in the 1960s and 1970s, including the development of clozapine, the first of the ‘atypical antipsychotic’ drugs, and imipramine, the first of the tricyclic class of antidepressants.
It?may have a synergistic effect with the sedating action of other drugs such as benzodiazepines, and thus respiratory depression may result with concomitant use. Care should be taken, especially if the latter drugs are given parenterally. View all 4.3 Toxicity LD50 in mice, rats (mg/kg):...