C. septicum Gas gangrene From the standpoint of metabolism, there appears to be a delineation between clostridia that are principally saccharolytic and those described as proteolytic. Genetic studies have demonstrated that strains falling into these two groups are unrelated with respect to DNA similarit...
Clostridium septicum is a Gram-positive anaerobic bacterium, which is the primary causal organism for traumatic clostridial myonecrosis; a fatal disease leading to necrotic death of human musculature (Abella et al., 2003). Alpha (α)-toxin is the primary virulence factor of C. septicu...
Clostridium septicum should be considered as potential pathogen in patients with sepsis and meningitis. Gram stain morphology in conjunction with severe sepsis can rapidly point into the direction of this pathogen. CNS infections manifest either as meningoencephalitis/cerebritis or as brain abscess. Entr...
septicumC. sordellii C. botulinum characteristics gram positive straight rods in singles and pairs, spores subterminal, lipase positive, species divided into 8 types (A, B and E in humans, A most prevalent) Foodborne botulism food contaminated with spores, which germinate under anaerobic conditions...
The most commonly encountered clinically clostridia are Clostridium perfringens, Clostridium clostridioforme, Clostridium ramosum, Clostridium butyricum, Clostridium innocuum, Clostridium septicum, Clostridium tertium, and Clostridium difficile [2]. Since the use of ribosomal 16S RNA genes as a new standard...
septicum seen in guinea pig liver impression smear. Gram-stain, × 2250 (H. A. McAllister). Bottom: Colonies of Cl. perfringens type C after 24-hr incubation on blood agar. Note zone of hemolysis caused by toxins of the organism. Cl. chauvoei Clostridium chauvoei grows poorly on blood ...
The genusClostridiumencompasses over 60 species of Gram-positive, anaerobic, spore-forming rods that cause a variety of infections in humans and animals. Strains ofClostridia, such asClostridium perfringens,Clostridium histolyticum,Clostridium septicum,Clostridium novyi, andClostridium sordellii, cause aggressi...
Clostridialmyositisin the horse is an often fatal disorder caused by infection by various toxin-producing clostridial species, which are large Gram-positive anaerobic bacilli.Clostridiumsepticumis the most common cause of clostridial myositis in horses, butClostridium perfringenstypes A to E,Clostridium ch...
Such species as C. septicum and C. histolyticum have been shown to infect the body through wounds causing gas gangrene. Many of such species are opportunistic in nature and were particularly prevalent in cases of battlefield injuries. *Gas Gangrene- Also known as clostridial myonecrosis, is a ...
K. The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin. Infect. Immun. 63, 340–344 (1995). CAS PubMed PubMed Central Google Scholar Leone, P. et al. X-ray and cryo-electron microscopy structures of monalysin pore-forming...