Clostridium scindens scindens梭菌
菌株类型: 闪烁梭菌,Clostridium scindens 存储人: LV Holdeman 分离来源: 人类粪便,纽约 产品目录号: 35704 其他保藏库编号: BCRC14551,ATCC 35704 ;DSM 5676 培养基: ATCC® Medium 2107: Modified Reinforced Clostridial ATCC® Medium 260: Trypticase soy agar/broth with defibrinated sheep blood 生长条件...
Clostridium scindens is a member of the gut microbiota and can convert cortisol to 11β-hydroxyandrostenedione (11β-OHA), which is a potent androgen precursor. However, the effect of C. scindens on PCa progression has not been determined. In this study, androgen-dependent PCa cells (LNCaP) ...
Clostridium scindens is a gut microbe capable of removing the side-chain of cortisol, forming 11β-hydroxyandrostenedione. A cortisol-inducible operon ( desABCD ) was previously identified in C. scindens ATCC 35704 by RNA-Seq. The desC gene was shown to encode a cortisol 20α-hydroxysteroid ...
“Clostridiumstrain 19” was later namedClostridium scindens(type strain ATCC 35704)[120].Clostridium scindens,particularly strain VPI 12708, are model organisms for the study of the complex bile acid 7α-dehydroxylation pathway responsible for conversion of primary to toxic secondary bile acids[...
The noncharacterized protein CLOSCI_02528 from Clostridium scindens ATCC 35704 was characterized as D-psicose 3-epimerase. The enzyme showed maximum activity at pH 7.5 and 60°C. The half-life of the enzyme at 50°C was 108 min, suggesting the enzyme was relatively thermostable. It was strict...
Clostridium scindensinducesC. difficilebiofilm To mimic the impact of DOC onC. difficilebiofilm formation in the context of the gut environment, we usedClostridium scindensATCC 35704 (Supplementary Table2), a bile acid 7α-dehydroxylating bacterium that belongs to the limited number of species of ...
[36]. Furthermore, the addition of a bacterial species,Clostridium scindens, containing bile-acid 7α-dehydroxylase activity was shown to ameliorate CDI in a mouse model [36]. No obvious associations could be made for OTUs indicative to moribund animals, in part because eight of the 13 were...
difficile. Organisms that produce secondary bile acids, such as Clostridium scindens, enhance C. difficile colonization resistance. Nontoxigenic C. difficile, which provides nutritional niche competition, may prevent CDI. Refinements to fecal microbiota transplantation (FMT) blur the line between pr...
(2016). Functional intestinal bile acid 7伪-Dehydroxylation by Clostridium scindens associated with protection from Clostridium difficile infection in a ... S Nicolas,D Lyne,B Markus,... - 《Frontiers in Cellular & Infection Microbiology》 被引量: 19发表: 2016年 Comparison among Fecal Secondary ...