Zeppa, Clonal B-cell population in a reactive lymph node in acquired im- munodeficiency syndrome, Diagn. Cytopathol. 37 (2009) 910e914.Cozzolino I, Nappa S, Picardi M, De Renzo A, Troncone G, Palombini L, Zeppa P: Clonal B-cell population in a reactive lymph node in acquired ...
cell state and their progressive activation during cell state switches. The intermediate population of scH/LP cells displayed a specific chromatin accessibility profile, with moderate accessibility of both scLP and scH markers. If this intermediate state was just a transient state of cells transitioning...
B cells and T cells are important components of the adaptive immune system and mediate anticancer immunity. The T cell landscape in cancer is well characterized, but the contribution of B cells to anticancer immunosurveillance is less well explored. Here
In all cases, PB immunophenotyping by flow cytometry revealed the presence of a clonal B-cell population with a Matutes score 0 to 2. Cells from all cases expressed B-cell antigens (CD19, CD20 strong), whereas they were consistently negative for the expression of CD10. Other individual mark...
The majority of these T-cell expansions have the phenotype of cytotoxic T cells (CD8(+)CD57(+) and perforin positive). Since V(beta) expansions can result from either a true clonal population or a polyclonal response, the clonality of CD8(+)TCRV(beta)(+) T cells was tested by TCRV(...
primitive, often referred to as leukemia stem cell (LSC), and differentiated cell types. The utilization of scRNA-seq presents an opportunity to precisely partition leukemia cell subgroups, and even further subdivide the LSC cell population, based on transcriptional variations at the single-cell ...
Miner BE, Stoger RJ, Burden AF, Laird CD, Hansen RS: Molecular barcodes detect redundancy and contamination in hairpin-bisulfite PCR. Nucleic Acids Res. 2004, 32: e135- Article PubMed PubMed Central Google Scholar Casbon JA, Osborne RJ, Brenner S, Lichtenstein CP: A method for counting ...
(C) Representative fluorescence-activated cell sorting plot of ZsG expression on PB CD45+ cells in 12-month-old WT and Tet2+/− mice. (D) Percentage of WT (n = 6) or Tet2+/− (n = 7) ZsG+ cells in PB T cells, B cells, myeloid cells, erythrocytes, and platelets. (E) ...
The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. 靶标信息 CCR2, a chemokine receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation. Resistance to ...
The mammalian brain contains many specialized cells that develop from a thin sheet of neuroepithelial progenitor cells. Single-cell transcriptomics revealed hundreds of molecularly diverse cell types in the nervous system, but the lineage relationships b