Effects of Clomipramine on Mixed Anxiety/Depression State Produced by Chronic Social Defeat Stress in Male MiceДмитрийАлександровичСмагин
The potential ability of the tricyclic anti-depressant to cause an increase in anxiety in adult following neonatal treatment with the drug has been investigated; no such anxiogenic actions were found in the social interaction test. Furthermore, the of that had received the drug as pups did not ...
Anafranil™ (clomipramine hydrochloride) Capsules USP is indicated for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). The obsessions or compulsions must cause marked distress, be time-consuming, or significantly interfere with social or occupational fu...
In order to answer this question, we have conducted a controlled study of clomipramine versus placebo in patients who have been suffering from residual depression for more than one year, in which we have measured its efficacy on impairment in social functioning.Method: - Following a 7 day ...
related to anxiety and stress levels and therefore to the social status of an animal, we tested the hypothesis that acute and chronic effects of clomipramine on sensorimotor gating are different in dominant versus subordinate rats, which might be responsible for conflicting results in past animal ...