In this trial 41 patients meeting the DSM-III-R criteria for Panic Disorder with and without Agoraphobia received 50 to 200 mg of clomipramine in a single-blind, flexible dose regimen for 14 weeks. Clinical evaluation and serum levels determinations were done at weeks 0 (baseline), 1, 5, ...
Clomipramine (Clomicalm) 是一种三环类抗抑郁药,能够有效阻断 5-HT 再摄取 (IC50:1.5 nM) ,可用于研究强迫症 (OCD) 及抑郁症。 规格价格库存数量 1 mg¥ 283现货 2 mg¥ 395现货 5 mg¥ 663现货 10 mg¥ 997现货 25 mg¥ 1,890现货 ...
A total number of 40 patients with a history of panic disorder were randomly assigned into two groups of 20 patients each. Hamilton anxiety rating scale and Standard Psychiatric Interview were methods for PD assessment. One group was treated with clomipramine hydrochloride (ANAFRANIL) 75 mg/day ...
In alleviating anxiety and panic disorder, both clomipramine doses were more efficacious than placebo for panic disorder and, to a lesser degree, for phobia. The lower dose was better tolerated and at least as effective as the higher dose, sometimes more so. These results indicate the ...
Panic DisorderHas been used effectively for the management of panic disorder† [off-label] with or without agoraphobia† [off-label].Major Depressive DisorderHas been used effectively for the management of major depressive disorder† [off-label]....
This study investigated the chronic use (6.3 +/- 0.5 years; mean +/- SEM) of therapeutic doses of clomipramine (57.0 +/- 8.0 mg/day) by outpatients with panic disorder/agoraphobia who were currently in remission to assess impairment of memory and psychomotor functions. In addition, the asso...
Clomipramine is more effective than imipramine, the generally accepted standard treatment for patients with panic disorder after 2 weeks' treatment, but after 6 or 10 weeks both drugs are similarly effective. Other double-blind studies have shown that clomipramine is more effective than placebo and ...
A dose-finding and discontinuation study of clomipramine in panic disorder Eighty-one patients with or without were treated with flexible doses of under single-blind conditions. Fifty-seven (70.3%) reached operational criteria for... F Lotufo-Neto,M Bernik,RT Ramos,... - 《Journal of Psychopha...
Paroxetine : a review of its pharmacology and therapeutic potential in the management of panic disorder. Paroxetine is the first selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor (SSRI) to be approved for the treatment of patients with panic d... RH Foster,KL Goa - 《Cns Drug...
Google Share on Facebook Thesaurus Medical Acronyms Wikipedia Related to clomipramine:Clomipramine hydrochloride clo·mip·ra·mine (klō-mĭp′rə-mēn′) n. A tricyclic antidepressant drug, C19H23ClN2, used in the form of its hydrochloride salt primarily to treat obsessive-compulsive disorder....