Prognosis of CLL in Asians When CLL develops in Asians it seems to have a worse prognosis than when it develops in persons of predominately European descent. This is so for untreated and treated persons suggesting a different disease biology. It is also possible CLL is diagnosed at a later ...
SF3B1 mutated MDS: Blast count, genetic co-abnormalities and their impact on classification and prognosis Article Open access 19 October 2022 Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial Article Open access 22 Dec...
Recurrent mutations refine prognosis in chronic lymphocytic leukemia. Leukemia 2015; 29: 329–336. 10 Guièze R, Robbe P, Clifford R, de Guibert S, Pereira B, Timbs A et al. Presence of multiple recurrent mutations confers poor trial outcome of relapsed/ refractory CLL. Blood 2015; 126: ...
When we evaluated the relative power of the 21FK score with the most used prognostic factors, the score was the most significant in both CLL cohorts. We conclude that the 21FK score represents a useful tool for distinguishing between good-prognosis and poor-prognosis CLL patients....
Infections have become the major cause of morbidity and mortality among patients with chronic lymphocytic leukemia (CLL) due to immune dysfunction and cytotoxic CLL treatment. Yet, predictive models for infection are missing. In this work, we develop the
Furthermore, it indicates that a higher migratory potential may be (or may contribute to) the reason why CD38+/ZAP-70+ patients with CLL are characterized by an unfavorable prognosis. How can the enhanced ability to recirculate be explained? The obvious answer is that the genes defined by ...
Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia Blood, 107 (2) (2006), pp. 742-751 View PDFView articleCrossrefView in ScopusGoogle Scholar 23 C Haferlach, F Dicker, S Schnittger, W Kern, T Haferlach Comprehensive genetic characterization of CLL: a...