Clinical trials: impact of intraarticular steroid injections on the progression of knee osteoarthritis. Osteoarthritis Cartilage. 1999;7:348-349.Raynauld JP. Clinical trials: impact of intraarticular steroid in
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis: A Phase II Randomized Sham-Controlled Trial The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) ...
Must have stage 2 or 3 knee osteoarthritis in last 6 months Must have taken NSAID for at least 3 months Must be 18 to 80 years of age Exclusion Criteria No other bleeding disorder No major conditions such as depression, cancer or kidney disease Must be willing to comply with study visits...
Clinical and preclinical evidence of mesenchymal stromal cell mechanisms of action on immunomodulation and chondroprotection in knee osteoarthritis. Solid arrows are used to demonstrate mechanisms for which there is supporting clinical evidence: dashed arrows indicate the relationship between immunomodulatory and...
BackgroundPain in primary knee osteoarthritis (OA) is the most disabling symptom. Osteoclast-initiated subchondral bone resorption, marrow edema, and synovitis collectively contribute to pain. Reduction of osteoclast activity by bisphosphonate may be effective in reducing pain.ObjectiveThis ...
Zhang, W.et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.Osteoarthritis Cartilage18, 476–499 (2010). ...
MECHELEN, Belgium and PARIS, Oct. 16, 2020 /PRNewswire/ -- Galapagos and Servier report topline results for ROCCELLA Phase 2 clinical trial with GLPG1972/S201086 in knee osteoarthritis patients
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural, inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific manner. This complexity has contributed to refractory responses to various tre
To (1) document pain location in medial tibiofemoral osteoarthritis (OA) using the patient-administered Photographic Knee Pain Map (PKPM); (2) compare pain severity, nature and likelihood of neuropathic-like symptoms, physical dysfunction and presence of symptoms at other sites across the most commo...
Close Related Articles Intensive Diet and Exercise and Knee Osteoarthritis Stephen P. Messier, PhD; Shannon L. Mihalko, PhD; Claudine Legault, PhD; et al. JAMA High-Intensity Strength Training, Knee Pain, and Knee Joint Compressive Forces in Adults With Knee Osteoarthritis—Reply Stephen P. ...