clinical trialsosteoarthritismesenchymal stem cellsintra-articular injectioncartilage regenerationOsteoarthritis (OA) is a whole-joint disease primarily characterized by the deterioration of hyaline cartilage. Current treatments include microfracture and chondrocyte implantation as early surgical strategies...
A Task Force of the Osteoarthritis Research Society International (OARSI) has previously published a set of guidelines for the conduct of clinical trials in osteoarthritis (OA) of the hip and knee1. Limited material available on clinical trials of rehabilitation in people with OA has prompted OARSI...
定价:$ 111.87 装帧:HRD ISBN:9781852338749 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 推荐 内容简介· ··· Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed ...
Seven published clinical studies (Table 1) and 14 ongoing clinical trials (Table 2) (as of September 2022) tested MSC-Exos as a therapeutic agent against different diseases, including acute respiratory distress syndrome (ARDS), kidney diseases, graft-versus-host disease (GvHD), osteoarthritis, str...
Our objective was to systematically assess the level of heterogeneity among all clinical trials and published studies regarding injections for knee osteoarthritis, in terms of treatment of interest, outcomes evaluated, and time points of outcome assessment. Methods: The Preferred Reporting Items for ...
Clinical trials in osteoarthritis. Author links open overlay panelL.M March, P.M BrooksShow more Add to Mendeley Share Cite https://doi.org/10.1136/ard.55.8.491Get rights and contentAccess through your organization Check access to the full text by signing in through your organization. Access...
Preclinical research and drug development primarily uses models of post-traumatic osteoarthritis (OA) in young individuals; its molecular pathophysiology could be different than the age-associated OA most commonly targeted in clinical trials Post-traumatic OA in mice is a valid model of the human dise...
“osteoarthritis”. The results were further filtered by “Clinical Trial” and “Randomized Controlled Trial”, resulting in 84 clinical trials. Additionally, recently published meta-analyses [76,77,78,79,80] were cross-referenced to ensure the inclusion of all relevant clinical studies, bringing ...
The drug's positive effects in mice and other animal models give researchers hope for its potential in upcoming trials with humans. This year, the team will launch a combined safety and preliminary efficacy clinical trial (Phases 1 and 2A) of R805/CX-011 for the treatment of osteoarthritis in...
An evidence based approach to the management of knee osteoarthritis: report of a Task Force of the Standing Committee for Inter... pmhdev - 《Centre for Reviews & Dissemination》 被引量: 532发表: 2003年 Therapeutic trials in digital osteoarthritis. A critical review Although common, hand ...