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In this context, we examined the effects of KPNA2 on cancer stem-like characteristics of ATC cells. The formation of ATC spheres was hindered obviously by the silence of KPNA2 (Fig. 8A, B). Moreover, this deletion of KPNA2 sharply impeded the expression of OCT4, NANOG and CD133 (Fig...
The effects of DNA methylation on gene activity primarily depend on different genomic regions, including CpG islands, intergenic regions, and genomic regions. Genome-wide analysis has shown that CpG islands are present in 60% of the promoter regions of the human genome [13], suggesting that dynam...
The effects of DNA methylation on gene activity primarily depend on different genomic regions, including CpG islands, intergenic regions, and genomic regions. Genome-wide analysis has shown that CpG islands are present in 60% of the promoter regions of the human genome [13], suggesting that dynam...
Ross DE, Levin ML (2004) Effects of Anaplasma phagocytophilum infection on the molting success of Ixodes scapularis (Acari: Ixodidae) larvae. J Med Entomol 41(3):476–483. https://doi.org/10.1603/0022-2585-41.3.476 Article PubMed Google Scholar Dunning Hotopp JC, Lin M, Madupu R, Cra...
Δ9-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects caused by the consumption of cannabis, both the marijuana-like action and the medicinal benefits of the plant. However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues...
Hypoxia often, though not always, increases the secretion of exosomes in various tumor cells through direct (cargo sorting, transport of MVBs and fusion with the plasma membrane) and indirect (metabolic reprogramming, induction of an acidic microenvironment, and effects on calcium and other regulatory...
effects on the fetus and offspring 15.7.3 Respiratory tract complications 15.7.4 Complications in diabetics 15.7.5 Myocarditis and pericarditis 15.7.6 Neurological complications 15.7.7 Toxic shock syndrome 15.7.8 Myositis, myoglobinuria and renal failure 15.8 Antivirals 15.8.1 Adamantanes 15.9 ...
Crockett AJ, Cranston JM, Moss JR, Alpers JH. Effects of long-term oxygen therapy on quality of life and survival in chronic airflow limitation. Monaldi Arch Chest Dis. 1999;54(2):193–6. CAS PubMed Google Scholar Eaton T, Lewis C, Young P, Kennedy Y, Garrett JE, Kolbe J. Long...
Flavonoids are a category of plant-derived compounds which exhibit a large number of health-related effects. One of the most well-known and studied flavonoids is kaempferol, which can be found in a wide variety of herbs and plant families. Apart from their anticarcinogenic and anti-inflammatory...