Category 0 includes drugs or drug uses that prevent the development of a disease when none exists; Category I, those that affect etiologic factors of a disease; Category II, those that affect specific disease processes; Category III, those that affect specific disease manifestations; Category IV,...
Absorption (effects of gastrointestinal pH, binding and adsorption, effects of gastrointestinal motility, effects on gastrointestinal absorption, changes in intestinal flora).Distribution (competitive protein binding sites, changes in tissue distribution). Metabolism (enzyme inhibition - phenobarbital, phenytoin...
prediction of a drug class (ATC code of the WHO) allows the evaluation of methods and descriptors for a well-characterized set of approved drugs. The... N Janette,G Bjoern-Oliver,E Jevgeni,... - 《Nucleic Acids Research》 被引量: 54发表: 2014年 Bin-Medical Computing A new drug classi...
The biopharmaceutical classification system acts as a guiding tool for development of various oral drug delivery technologies.Introduction:The oral route of drug administration is the route of choice for the formulators and continues to dominate the area of drug delivery technologies. However, though ...
The U.S. Food and Drug Administration (FDA) approves new drugs every year. Drug targets are some of the most important interactive molecules for drugs, as they have a significant impact on the therapeutic effects of drugs. In this work, ... Hui-Heng,Lin,Le-Le,... - 《Scientific Report...
It is produced by a strain of S. bergedorf and inhibits a wide range of Salmonella serotypes from many different Kaufmann-White (K.W.) group... Atkinson,Nancy - 《Immunology & Cell Biology》 被引量: 10发表: 1966年 Mutant Drug Resistant Factors of High Transmissibility The isolation of ...
(PLS-DA) indicated that in comparison with the control group, the media amino-acid consumption profiling can distinguish the two anticancer drugs with different mechanisms, which provides a new perspective for the pre-classification of drug action mechanisms during the screening of new anticancer ...
This article examines some pharmacologic properties of these drugs to clarify their terminology and their classification and to provide a rationale for their clinical use. Studies with nifedipine show quantitatively that the therapeutic effect in angina is related to the interaction of this drug with ...
Computational approaches, including global model-based and local model based, are able to screen DDI candidates among a large number of drug pairs by utilizing preliminary characteristics of drugs (e.g. drug chemical structure). However, global model-based approaches are usually slow and don't ...
Drug-related problem (DRP) is an event or circumstance involving drug therapy that actually or potentially interferes with desired outcomes (e.g., the effect of the drug treatment is not optimal, Table 1) [20]. DRPs occur or have the potential to happen, because of a prior event or even...