Background Class 1C antiarrhythmic drugs (AADs) are effective first‐line agents for atrial fibrillation (AF) treatment. However, these agents commonly are avoided in patients with known coronary artery disease (CAD), due to known increased risk in the postmyocardial infarction population. Whether ...
Figure 6. Examples of class 1c antiarrhythmics. • Toxicity: The toxicity of class 1c drugs includes arrhythmias and cardiovascular depression. Show moreView chapterExplore book Drug Class Analysis Tom Brody, in FDA's Drug Review Process and the Package Label, 2018 ...
Cardioprotective effects of various class I antiarrhythmic drugs in canine hearts. J Am Coll Cardiol. 1989 Jul; 14 (1):219–224.Hanaki Y, Sugiyama S, Hieda N, Taki K, Hayashi H, Ozawa T (1989) Cardioprotective effects of various class I antiarrhyth- mic drugs in canine hearts. J Am ...
Local anesthetic and antiarrhythmic drugs act upon NaV1.5 to modulate ... A Beyder,PR Strege,C Bernard,... - 《Channels》 被引量: 14发表: 2012年 Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. The voltage-gated Nav1.5 channel is essential for...
In the dose-ranging evaluation of dolasetron, computer-generated ECGs revealed clinically asymptomatic prolongations of ECG intervals. We performed a clinical trial in which the possible changes in ECG intervals following a single 3-mg i.v. injection of granisetron and an injection of either ...
PJ-291 Clinical Efficacy of Bepridil for Class I Antiarrhythmic Drug-Induced Atrial Flutter(Arrhythmia, therapy-19, The 71st Annual Scientific Meeting of t... H Hayashi,M Sumiyoshi,M Kawamura,... - Japanese Circulation Journal-english Edition 被引量: 0发表: 2007年 PJ-291 Clinical Efficacy of...
Since the use of cinchona bark to treat heart palpitations in the 1700s, antiarrhythmic drug therapy has developed with the discovery of new compounds and the identification of ionic, cellular, and tissue mechanisms of action. Classifications have been developed that organize the large amount of inf...
象其他类III antiarrhythmics, vernakalant块心房的钾渠道,从而延长复极化[119-121]。 翻译结果5复制译文编辑译文朗读译文返回顶部 正在翻译,请等待... 相关内容 aso l have to find different ways to do little acts of 如此l必须发现不同的办法少许做行动[translate] ...
Bispidin derivatives as class III antiarrhythmics 专利名称：Bispidin derivatives as class III antiarrhythmics 发明人：LUBISCH, WILFRIED, DR.,BINNIG, FRITZ, DR.,VON PHILIPSBORN, GERDA, DR.申请号：EP88115299.5 申请日：19880917 公开号：EP0308843B1 公开日：19931215 专利内容由知识产权出版社提供 摘...
Pentisomide (CM 7857): A New Class I Antiarrhythmic AgentAntiarrhythmic effectCM7857PentisomidePharmacokineticsPharmacologyToxicologydoi:10.1111/j.1527-3466.1993.tb00268.xShiwen YuanS. Bertil OlssonCardiovascular Drug Reviews