Immunogen Caspase 8/p43/p18 fusion protein Ag20524 种属同源性预测 Host / Isotype Mouse / IgG2b Class Monoclonal Type Antibody Full Name caspase 8, apoptosis-related cysteine peptidase Synonyms CASP8, Caspase 8, CASP-8, CAP4, Apoptotic protease Mch-5 Calculated Molecular Weight 538 aa, 62 kD...
CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc Natl Acad Sci U S A 1997;94:10717-22.Inohara N, Koseki T, Hu Y, Chen S, Nunez G. CLARP, a death effector domain-containing protein interacts with caspase- 8 and regulates apoptosis....
Caspase-8 and Bid activation appeared to be downstream of mitochondria, because Bcl-2 overexpression suppressed both events, suggesting that infected 17Cl-1 cells might have activated a receptor-mediated "type II" signaling pathway, in which primary and low levels of receptor-mediated pathway ...
Inohara N,Koseki T,Hu Y,Chen S,Nunez G.CLARP,a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis.Proceedings of the National Academy of Sciences of the United States of America. 1997Inohara N , Koseki T , Hu Y , Chen...
Binding of Bid and caspase-8 to CL-containing large unilamellar liposomes (LUVs).Olivier, JalmarLiberty, FrançoisMoutalAnaJesus, GarcíaSáezMark, PerryThierry, GranjonFrançois, GonzalvezEyal, GottliebJesus, AyalaSanmartinBeate, KlösgenPetra, Schwille...
Hasegawa, Imamura R, Kinoshita T, Matsumoto N, Masumoto J, Inohara N, Suda T: ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP. J Biol Chem 2005, 280:15122e15130Hasegawa M, Imamura R, Kinoshita T, Matsumoto N, Masumoto J...
A caspase-8/inhibitor complex has been crytallized, and the three dimensional x-ray crystal structure of a recombinant human caspase-8 has been solved at atomic resolution (1.2 ANGSTROM ), and substrate binding pocket has been identified. The x-ray crystal structure is useful for solving the ...
ASC-mediated NF-B activation leading to IL-8 production re- quires caspase-8 and is inhibited by CLARP. J. Biol. Chem. 280: 15122-15130.Hasegawa M, Imamura R, Kinoshita T, Matsumoto N, Masumoto J, Inohara N, et al. ASC-mediated NF-kappaB activation leading to interleukin-8 ...
Antibodies against caspase-8, their preparation and useThe invention relates to antibodies to a specific region in caspase-8, and to their use.doi:EP1423429 A2Tanya GoncharovGanesh KolumamDavid Wallach
Murine coronavirus-induced apoptosis in 17Cl-1 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and bid cleavage. Virology. 2002;302(2):321-32.Chen, C. J., and S. Makino. 2002. Murine coronavirus-induced apoptosis in 17Cl-1 cells involves a ...