Summary and conclusions A significant percentage of CKD stage 4 patients attending a renal management clinic (RMC) showed non-progression or improvement in their kidney function. Although only few stage 5 CKD patients had improvement in their eGFR, 32% of them maintained their eGFR on conservative...
虽然最初认为IgA肾病的病程为良性,但目前发现多达50%的受累患者往往会在20-25年的观察期里缓慢进展为终末期肾病(end-stage renal disease, ESRD)[7]。其余患者进入持续的临床缓解期,或出现持续性低度血尿和/或蛋白尿。虽然可能难以预测一些患者的预后情况,但现已确定了肾病进展的重要危险因素。(参见下文‘疾病进展...
慢性肾脏病(chronic kidney disease,CKD)已成为世界性的公共健康问题,CKD患者最终会进展至终末期肾病(end stage renal disease,ESRD),需要长期依赖透析或肾移植维持生命,不仅严重降低患者的生活质量,也给社会和家庭带来了沉重的经济负担。 慢性肾脏病进入疾病的发展3期以后,已不能临床治愈,也就是普通大众理解的慢性肾衰...
Results During a median follow-up of 1.57year (range 0.5–8.7year) of stage 4 patients, eGFR improved in 10.6%, showed mild improvement in 24.2%, was stable in 27.5%, showed slow progression in 28.8% and rapid progression in 8.9% of patients. During a median follow-up of 1.4year (...
慢性肾脏病(chronic kidney disease,CKD)已成为世界性的公共健康问题,CKD患者最终会进展至终末期肾病(end stage renal disease,ESRD),需要长期依赖透析或肾移植维持生命,不仅严重降低患者的生活质量,也给社会和家庭带来了沉重的经济负担。 慢性肾脏病进入疾病的发展3期以后,已不能临床治愈,也就是普通大众理解的慢性肾衰...
慢性肾脏病(chronic kidney disease,CKD)已成为世界性的公共健康问题,CKD患者最终会进展至终末期肾病(end stage renal disease,ESRD),需要长期依赖透析或肾移植维持生命,不仅严重降低患者的生活质量,也给社会和家庭带来了沉重的经济负担。 慢性肾脏病进入疾病的发展...
Background and objectives The association of individual BP components with changes in eGFR in patients with late-stage CKD is unknown. The objectives of our study were to examine the associations of systolic BP, diastolic BP, and pulse pressure with continuous temporal changes in eGFR and an eGFR...
方法:收集 78 例 CKD 患者同一时 间段的血清肌酐( SCr) , 血清胱抑素 C ( CysC) 和99m Tc⁃DTPA 肾动态显像资料, 用三种 CKD⁃EPI 方程估算 GFR ( eGFR) 与99m Tc⁃DTPA 肾动态显像检测的 GFR 参考值( rGFR) 的误差 ΔSCr ,ΔCysC 与ΔSCr/ CysC ,作 P⁃P 图,Pearson 相关 分析与 ...
CKD was staged according to the definition of K/DOQI guidelines24, and the estimated glomerular filtration rate (eGFR) was calculated using the equation of the 4-variable Modification of Diet in Renal Disease (MDRD) study. We excluded patients suffering from CKD stage 5 or those who were lost...
Excess mortality occurs across the full spectrum of CKD stages and those with a CKD diagnosis have a greater probability of dying than developing end-stage kidney disease [4]. Cardiovascular (CV) disease remains a leading cause of death in CKD patients, who experience a high burden of ...