PD-L1 expression, Non-small cell lung cancer, Circulating tumor cells, Liquid biopsy, Checkpoint inhibitor therapyWe evaluated the analytical and clinical performance of a novel circulating tumor cell (CTC)-based blood test for determination of programmed death ligand 1 (PD-L1) protein expression ...
The CELLSEARCH® CTC Test is:The first and only clinically validated, FDA-cleared blood test for enumerating circulating tumor cells (CTCs). CTCs are cancer cells that detach from a primary tumor and travel through the bloodstream or lymphatic system to other parts of the body. A“liquid biop...
Circulating tumour cells (CTCs) can be captured from a simple blood test and their molecular characterization can provide vital insights into tumour heterogeneity Advances in single-cell genomic profiling have enhanced the ability to interrogate CTCs for 'actionable' aberrations and emerging resistant subc...
collective cell migration and cells with tumour-initiating capacity within the circulation. Advances in single-cell molecular analysis are enhancing our ability to explore mechanisms of metastasis, and the combination of CTC and cell-free DNA assays are anticipated to provide invaluable blood-borne...
Multistep process of cancer metastasis. The complex metastatic process includes tumor cell invasion in the primary site, intravasation into circulation, survival in the circulation as CTCs and interaction with blood cells, extravasation from the circulation, attachment to and colonization of the metastat...
These observed discrepancies may be the cause of tumor cell persistence and therapeutic failure in the adjuvant setting. In the present study we have used a RT-PCR-based approach to examine the presence of CTCs in peripheral blood of patients with primary breast cancer, to assess the correlation...
The CellSearch®System is the first diagnostic test used to automate the capture and detection of CTCs, tumor cells that have detached from solid tumors and entered the patient’s blood. The CellSearch®System assesses CTCs to determine the prognosis and overall survival of ...
RNA-Seq of Circulating Tumor Cells in Stage II-III Breast Cancer(II-III期乳腺癌中循环肿瘤细胞的RNA-Seq) 热度: Morphological Differences between Circulating Tumor Cells from Prostate Cancer Patients and Cultured Prostate Cancer Cells 热度: detection of circulating tumor cells in peripheral blood from ...
The Cell-Search® system (Veridex) is the most common positive selection approach. It is currently the only clinically validated, FDA-cleared system for the identification, isolation, and enumeration of circulating tumor cells (CTCs) from a simple blood test. It is based on the use of antibod...
A. et al. Profiling of circulating tumor DNA for noninvasive disease detection, risk stratification, and MRD monitoring in patients with CNS lymphoma. Blood 138, 6 (2021). Article Google Scholar Bobillo, S. et al. Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors ...