Recently, circulating follicular helper T cells (cTfh) have been identified in peripheral blood; this facilitates the study of cTfh as potential biomarker in renal transplantation. With this background, the aims of our study are: (1) to show the capacity of cTfh to differentiate B ce...
Objectives T follicular helper (Tfh) cells are the principal T helper cell subset that provides help to B cells for potent antibody responses against various pathogens. In this study, we took advantage of the live゛ttenuated yellow fever virus (YFV) vaccine strain, YFD, as a model system ...
T follicular helper (TFH) cells, a CD4+ T cell subset, have been identified as an essential orchestrator of B cell proliferation, differentiation and antibody production within the germinal centre (GC) (Crotty, 2011; Qi, 2016). Circulating CD4+CXCR5+ TFH (cTFH) cells in peripheral blood ...
a faster increase in lymphocyte counts and a higher frequency of CXCR3+T follicular help (TFH) cells compared with COVID-19-convalescent individuals who experienced non-severe
This is the first in-depth characterization of ZEBOV-GP specific, circulating follicular T cells (cTfh). Since antibody titers correlated with protection in preclinical models of ZEBOV infection, Tfh were predicted to correlate with protection. Indeed, the ZEBOV-specific cTfh data correlated with ...
circulating follicular helper T cellsCXCR5CXCR3–PD-1+Objectives: Which helper CD4+ T cell subset contributes to autoantibodies generation and severity of end-organ involvement in lupus patients remains to be explored. Our research aims to investigate the roles of circulating Tfh (cTfh) cell ...
Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis. Int Immunopharmacol 2017;... Zun-...
Circulating T follicular helper (cTfh) cells have been identified as counterparts of germinal center Tfh (GC Tfh) cells in humans and can support T-dependent B cell maturation and antibody production in vitro. However, the role of cTfh cells in neutraliz
Circulating follicular T helper cells are possibly associated with low levels of serum immunoglobulin G due to impaired immunoglobulin class-switch recombination of B cells in children with primary nephrotic syndrome 来自 Semantic Scholar 喜欢 0 阅读量: 40 作者:...
cells culminate in a refined and long-lived antibody response. The critical go-between in this cellular trio is the follicular helper T (T FH ) cell that liaises first with the DC, before migrating to the B cell follicle for repeated interaction with B cells 1 . Such T FH cells bear a...