We propose that the level of circulating CD34+ cells provides a marker of vascular risk associated with cognitive impairment, and that differences in the pathobiology of Alzheimer's- and vascular-type cognitive impairment may be mirrored in levels of circulating CD34+ cells in these patient ...
Shimizu Y, Sato S, Koyamatsu J, Yamanashi H, Nagayoshi M, Kadota K, Maeda T. Circulating CD34-positive cells, glomerular filtration rate and triglycerides in relation to hypertension. Atherosclerosis. 2015; 243:71-6. doi: 10.1016/j.atherosclerosis.2015.08.035....
A significant positive association between triglycerides and blood pressure exists among those with lower, but not higher, circulating CD34-positive cells. The level of circulating CD34-positive cells acts as a determinant factor for the association between triglycerides and blood pressure. 展开 关键词:...
After 7 days, CD34+ cells were effectively expanded in a serum-free culture medium. Expanded CD34+ cells were also increasingly positive for cell surface markers of VE-cadherin, VEGF receptor-2, and Tie-2. The expression of proangiogenic growth factors and adhesion molecules in expanded CD34+ ...
Aims Circulating progenitor cells such as CD34+ cells play a key role in maintenance of vascular endothelial function and neovascularization, and a decrease in the number of CD34+ cells is associated with cardiovascular disease. However, the contribution of circulating progenitor cells to microvascul...
Cells were stained for CD34ϩ using the International Society of Hematotherapy and Graft Engineering (ISHAGE) definition for identifying CD34ϩ, i.e. cells gated on CD45ϩ dim/low side scatter CD34ϩ positive cells (17). Samples were acquired using a FACS Calibur flow cytometer (BD ...
RA had significantly decreased numbers of cells expressing CD34 (0.21±0.29×106/l) compared with normal subjects (0.81±0.36×106/l)(P<0.001). This low number of CD34+ cells in RA resembles the case of AA (0.39±0.73×106/l). In light-scatter analysis, the CD34+ cells of RA patients...
We scored absolute numbers of circulating CD34 + cells by a highly sensitive triple-color flow cytometric analysis using CD45 monoclonal antibody, CD34 monoclonal antibody and propidium iodide. Forty-one patients with MDS (RA: 27, RARS: 1, RAEB: 6, RAEB-t: 3,CMML: 4), 12 patients with ...
The bilineage potential of CD34−Lin−CD45−CD133− cells was determined at the single-cell level in vitro and was confirmed by transplantation into NOD/SCID mice. In vivo, CD34−Lin−CD45−CD133− cells showed the ability to reconstitute hematopoietic tissue and to generate ...
Functional activity of murine CD34+and CD34 hematopoietic stem cell populations The transmembrane glycoprotein CD34 is expressed on human hematopoietic stem cells and committed progenitors in the bone marrow, and CD34-positive selectio... D.Scott,Donnelly,and,... - 《Experimental Hematology》 被引量:...