(B) The bacterial chromosome may be organized into topological domains by the interaction of DNA with proteins that are associated with the bacterial membrane. A number of reactions involving DNA, such as replication, may occur at the membrane. (C) A linear DNA molecule can form a topolo...
Chromosome Form and Number Bacterial DNA has been found in both circular and linear forms. For Escherichia coli, chromosomal circularity is supported by three lines of evidence. First, circles were observed when radioactively labeled DNA was extracted from cells and then examined by autoradiography. ...
commonly observed in malignant tumors and congenital diseases [77]. Small-sized eccDNAs are closely associated with late-stage apoptosis during chromosome breakage, with DNA ligase 3 playing a crucial role in the generation of nucleosome
Circular chromosomes with centromere DNA comprise recombination sites flanking a region with bacterial replication DNA and a recombinase transcription unit. Circular chromosomes without bacterial replication DNA are formed by removing bacterial replication DNA from a circular chromosome by action of a ...
a招投标机制 Incurs the bid mechanism[translate] athe hereditary material of most bacteria exists in the form of a single circular strand of DNA designated as the bacterial chromosome. 多数细菌遗传性材料存在以脱氧核糖核酸的形式一条唯一圆子线被选定作为细菌染色体。[translate]...
A major challenge in constructing artificial cells is the establishment of a recursive genome replication system coupled with gene expression from the genome itself. One of the simplest schemes of recursive DNA replication is the rolling-circle replicati
The first Lactobacillus delbrueckii ssp. bulgaricus genome sequence revealed the presence of a very large inverted repeat (IR), a DNA sequence arrangement which thus far seemed inconceivable in a non-manipulated circular bacterial chromosome, at the repl
Extrachromosomal circular DNA (eccDNA) is considered a circular DNA molecule that exists widely in nature and is independent of conventional chromosomes. eccDNA can be divided into small polydispersed circular DNA (spcDNA), telomeric circles (t-circles),
During the test, we found that even the largest bacterial chromosome longer than 8,000,000 bp can be loaded and displayed comfortably on a computer with 512 Mb of memory and a moderate 3D graphics card. 3D Genome Tuner gives user privilege to set the color of any item and the radius of...
The direct imaging of widened liveE. colicells presented here provides a unique window to understanding the bacterial genome organization. By decoupling DNA replication and cell growth in widened bacteria, we were able to visualize the circular shape of the chromosome in liveE. colicells. We found...