Circadian rhythm and cell cycle are the two main rhythmic and cyclical activities in living organisms,where expression of a series of genes to form a regulatory network. Recent studies have revealed that various clock rhythm factors controlled cell cycle procession by regulating the expression of cell...
(1972) Circadian rhythm in the cell cycle time of the mouse intestinal epi- thelium. J. interdiscipl. Cycle Res. 3,39.Sigdestad, C.P. & Lesher, S. ( 1972 ) Circadian rhythm in the cell cycle time of the mouse intestinal epithelium . J. interdiscipl. Cycle Res. 3 , 39 ....
Disruption of 24-h rhythms leads to cardiovascular disease, including heart failure, myocardial infarction and arrhythmias. 24-h rhythms are present in the development, risk factors, incidence and outcome of cardiovascular disease. Cardiovascular disease leads to disrupted circadian rhythm and sleep proble...
Assuming that periodic control represents the normal circadian rhythm regularly reset by dark-light alternance, and no control (i.e., constant death rates) represents a disrupted circadian clock, we were expecting from the aforementioned experiments on laboratory rodents the converse, i.e., higher ...
cell cyclecircadian cycleSome key elements are common to two fundamental periodic regulatory processes; the circadian cycle and the cell cycle. Underlying mechanisms of coordination between the two processes are critical for proper cellular functioning and physiology. Disruption in the mechanisms of one ...
Rheostatic balance of circadian rhythm and autophagy in metabolism and disease. Front. Cell Dev. Biol. 8, 616434 (2020). Article PubMed PubMed Central Google Scholar Manella, G. et al. Hypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignment....
cir·ca·di·an rhythm (sər-kā′dē-ən) A daily cycle of biological activity based on a 24-hour period and influenced by regular variations in the environment, such as the alternation of night and day. Did You Know?Why do you sometimes wake up on time even if your alarm clock...
Whenscientistsexaminedthepair'sDNA,theyfoundamutationinagenecalledDEC2,whichgovernscellproductionandcircadianrhythm. 科学家们通过检测这对DNA发现一个叫作DEC2发生了突变,而这个基因正是控制细胞分裂和生理周期的。 article.yeeyan.org 3. NowIthinkthere'samuchbetterawaytoaccomplishthiswithoutthe leastbitofharmdone...
Circadian rhythm disruption increased cell proliferation and cell division, which are tightly linked to tumor. Many cancer treatments seek to arrest progression through the cell cycle. The researchers found that the tumor-fighting ability of one drug that arrests cell cycle progression varied with time...
To understand aging impact on the circadian rhythm, we screened for factors influencing circadian changes during aging. Our findings reveal that LKRSDH mutation significantly reduces rhythmicity in aged flies. RNA-seq identifies a significant increase in