Chronic inflammationRace-ethnic disparitiesBiomarkersThe incidence of small vessel-type (lacunar) ischemic strokes is greater in African-Americans compared to whites. The chronic inflammatory changes that result from lacunar stroke are poorly understood. To elucidate these changes, we measured serum ...
inflammation (redirected fromchronic inflammation bowel disease of sheep) Thesaurus Medical Encyclopedia in·flam·ma·tion (ĭn′flə-mā′shən) n. 1.The act of inflaming or the state of being inflamed. 2.A localized protective reaction of tissue to irritation, injury, or infection, cha...
It has been speculated that these immunological changes may induce the loss of tolerance and/or trigger chronic inflammation. In particular, molecular mimicry, bystander activation and epitope spreading are well-established proposed mechanisms to explain this correlation with the likely contribution of HLA...
Chronic stress activates the sympathetic nervous system (SNS) and hypothalamic–pituitary–adrenal (HPA) axis to aggravates tumorigenesis and development. Although the importance of SNS and HPA in maintaining homeostasis has already attracted much attention, there is still a lot remained unknown about th...
Inflammation sensitive transmembrane TJ protein, Claudin-5 increased at 1 hour followed by upregulation of downstream ZO-1 at 6 hours. In human CKD arteries, we found that claudin-5 was downregulated (Fold changes, FC, 2.16) while ZO-1 was upregulated (FC=2.17). Furthermore, cell viability...
Cerebral small vessel disease and chronic kidney disease (CKD): results of a cross-sectional study in community-based Japanese elderly. Inflammatory processes are involved in the pathogenesis of atherosclerosis. Inflammation has been known as a risk factor for coronary heart disease, wherea... M Wa...
Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation. Intensive Care Med. 2003;29:1798–801. PubMed Google Scholar Filip AT, Balacescu O, Marian C, Anghel A. Microbiota small RNAs in inflammatory bowel disease. J ...
In this cohort, adventitia and intimal plaque of total occlusions were the prevalent zones of inflammation and neovascularization. Furthermore, the results revealed in CTOs of all ages a close relation between cellular inflammation and vessel wall neovascularization in terms of location and intensity ...
small vessel disease and highlighted the frequency of microvascular calcification in those brains [7]. Pathways that promote cerebral small vessel disease in the uremic milieu include loss of calcium/phosphorus homeostasis, blood pressure variability, retention of vascular toxins, and chronic inflammation ...
Living long is a biological process characterized by progressive alterations in tissue/organ function, often associated with increased risk of chronic diseases. Among major theories...