leukemiachronic myelomonocyticdiagnosisA four-year-old child with recurrent infections and increasing hepatosplenomegaly over a three-year period was evaluated. Increased numbers of myeloid precursors packed the bone marrow and infiltrated the peripheral blood. A diagnosis of chronic myelogenous leukemia (...
Called also monocytic leukemia. acute myeloblastic leukemia 1. a common kind of acute myelogenous leukemia, in which myeloblasts predominate; it usually occurs in infants and middle-aged to older adults. Two types are distinguished; those that have minimal cell differentiation or maturation and ...
Phase II study of pevonedistat (P) + azacitidine (A) versus A in patients (pts) with higher-risk myelodysplastic syndromes (MDS)/chronic myelomonocytic leukemia (CMML), or low-blast acute myelogenous leukemia (LB AML) (NCT02610777). J Clin Oncol. 2020;38:7506. Article Google Scholar ...
IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell 2011; 20: 661–673. CAS PubMed PubMed Central Google Scholar Ballerini P, Struski S, Cresson C, Prade N, Toujani S, Deswarte C et al. RET fusion genes are ...
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm driven by BCR-ABL1 oncoprotein, which plays a pivotal role in CML pathology, diagnosis, and treatment as confirmed by the success of tyrosine kinase inhibitor (TKI) therapy. Despite a
Recombinant human interferon alpha-2 and juvenile chronic myelogenous leukemia: cell receptor binding, enzymatic induction, and growth suppression in vitro Recombinant human leukocyte interferon (HuIFN alpha 2) was studied to determine its potential as a therapeutic agent for the lethal monocytic malignanc...
To better understand the Philadelphia-negative (Ph-) chronic myeloid leukemia (CML) and its relationships with Philadelphia-positive (Ph+) CML and chronic ... P, Martiat,JL Michaux,J, Rodhain - 《Blood》 被引量: 561发表: 1991年 Philadelphia chromosome-negative chronic myelogenous leukemia and...
Chapter Hill, J.M.; Meehan, K.R. Postgraduate Medicine 106(3): 149-152; 157-159 1999 ISSN/ISBN:0032-5481 10494272 10.3810/pgm.1999.09.686 045517281 Download citation: Text | BibTeX | RIS Article emailed within 0-6 h Payments are secure & encrypted ...
leukemia in periods ranging from 2 to 36 months. As a final diagnosis chronic myelogenous leukemia (CML) was established in 10, with accompanying blast crisis in 6 and acute non-lymphocytic leukemia (ANLL) in 11 cases. Histomorphology of the resin embedded cores of bone marrow showed hyper...
Chronic myelogenous leukemia with p190BCR-ABL expression: the poor outcome of CML patients, not all major-route ACAs or ABL1 mutations detected at diagnosis or acquired during therapy are equally prognostically significant in TKI era.12–15 The data in this study indicate that the e1a2 ...