Chronic lymphocytic leukaemia articles from across Nature Portfolio Atom RSS Feed Chronic lymphocytic leukaemia (CLL) is a progressive, malignant disease of the blood-forming organs, marked by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. ...
Chronic lymphocytic leukaemia (CLL) is the commonest leukaemia in the Western world. It is a disease of the elderly and is usually incurable except in a minority of patients suitable for allogeneic haematopoietic stem cell transplantation. Many CLL patients are asymptomatic and the condition is ...
B-cell chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy that is characterized by a monoclonal expansion of mature CD5+ B-cells. The morphology, immunophenotype and even gene expression profile of the malignant B-cells is relatively homogeneous, in contrast to the marked variability...
lymphoblastic leukaemia───淋巴细胞白血病 双语使用场景 Lymph node enlargement occurs early inchronic lymphocytic leukemia.───慢性淋巴细胞性白血病,出现淋巴结肿大较早。 Using the test, they found thatchronic lymphocytic leukemia(CLL) is an "easy mark" for the experimental drug ABT-737.───他们...
The typical patient with chronic lymphocytic leukemia (CLL) is old. For proper choice of therapy, older adults with CLL in need of treatment must be examined towards biological characteristics of their disease (presence or absence of 17p deletion or TP53
Chronic lymphocytic leukemia (CLL), the most frequent type of leukemia in adults, is a lymphoproliferative disease characterized by the clonal expansion of mature CD5+B cells in peripheral blood, bone marrow, and secondary lymphoid tissues. Over the past decade, substantial advances have been made...
2. Laboratory Diagnosis of Chronic Lymphocytic Leukaemia 3. The Clinical Presentation of CLL 4. Prognostic Markers 5. Guidelines for Diagnosis, Indications for Treatment, Response Assessment, and Supportive Management of Chronic Lymphocytic Leukemia: The 2018 Update 6. Initial Therapy of Chronic ...
Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. We characterized the whole genome, epigenome and transcriptome, combined with single...
Schubauer-Berigan MK, Daniels RD, Fleming DA, Markey AM, Couch JR, Ahrenholz SH, Burphy JS, Anderson JL, Tseng CY. Chronic lymphocytic leukaemia and radiation: findings among workers at five US nuclear facilities and a review of the recent literature. British journal of haematology. 2007 Dec...
Blakemore SJ, Clifford R, Parker H, Antoniou P, Stec-Dziedzic E, Larrayoz M, et al. Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial. Leukemia. 2020;34:1760–74. ...