In the term of "chronic ischemic heart disease" a series of different nosological, physiopathologic and etiological forms are included, which can differ even considerably in their therapy. Among these, stable, unstable, variant and microvascular angina are the most common, as well as the various...
CCI may lead to progressive cognitive impairment that is considered as a prelude to neurodegenerative diseases, including dementia and Alzheimer's disease (AD). Endothelial progenitor cells (EPCs) have been implicated in vascular repair in ischemic cerebrovascular diseases, primarily by differentiating ...
It is in general difficult to predict which patient with stable ischemic heart disease will receive interventional or surgical revascularization in the long term, after initially being treated with optimal medical therapy (OMT). In the occluded artery trial (OAT), late opening of infarct-related art...
The results of the univariate Cox regression models showed that older age; a history of hypertension; a history of ischemic heart disease; higher levels of SBP, HbA1c, SCr, urea, and potassium; lower levels of DBP, eGFR, ALT, and albumin; and the use of diuretics, ACEIs, ARBs, beta-...
(ALX/FPR2). Following myocardial infarction, FPR2-deficient mice had decreased numbers of resolving macrophages and increased numbers of neutrophils at the site of injury, indicating that FPR2 could play an important role in resolution following ischemic injury [191]. Resolvin E1 (RvE1), an ...
showed that miR-6918-5p prevented renal tubular cell apoptosis by targeting MBD2 in ischemic AKI (J. Pan et al., 2022). In addition, a recent study demonstrated that miR-486-5p provides protection against ischemic AKI in rats, preventing the progression to chronic kidney disease and vascular...
Lacunar infarcts were defined as having ≥ 1 ischemic infarction (< 1.0 cm) in the deep white matter, the basal ganglia or pons [32]. CMBs were defined as having ≥ 1 small (0,2 − 0,5 cm) hypointense lesion [32], using the SWAN sequence. Cortical atrophy was def...
The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. Kidney Int... F Fani,G Regolisti,M Delsante,... - 《Journal of Nephrology》 被引量: 16发表: 2017年 The specificity of acute and chronic microvascular alterations in renal allografts The ...
Under the context of chronic ischemia, PEI-antagomir-induced inhibition of miR-3074-1-3p attenuated physical coupling of endothelial cells and OPCs and mitigated demyelination dependent on Cav-1, further emphasizing the core value of Cav-1 in therapeutics for ischemic white matter disease. ...
coronary flow increase (> 50%) after PCI; (7) ischemic post-PCI STDE-CFC was associated with lower post-PCI STDE-derived hyperemic coronary flow and higher microvascular resistance in LAD territory, while post-PCI FFR was non-different between ischemic and non-ischemic post-PCI STDE-CFC ...