Biology definition: Chromatin is a substance made up of DNA or RNA and proteins, such as histones. It condenses during cell division (mitosis or meiosis) and becomes a chromosome. Chromatins are“unwound” condensed structures whereas chromosomes are highly packaged and more condensed than chroma...
Define chromatin. chromatin synonyms, chromatin pronunciation, chromatin translation, English dictionary definition of chromatin. n. A complex of nucleic acids and proteins, primarily histones, in the cell nucleus that stains readily with basic dyes and
A technically simple examination of an interphasic nucleus reveals the condition of the system of sex chromosomes. The X chromatin is found more or less frequently in women in the nuclei of all tissue cells, for example, in 15–60 percent of the nuclei in the epithelial cells of the oral ...
Chromatin is a type of genetic material composed ofDNAand proteins. It helps to pack the DNA into a small voluminous structure that can be contained within the nucleus. It condenses to form the chromosomes during eukaryotic cell division. Cells are the basic functional units of life. The major...
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The classic definition of heterochromatin originated from staining mitotic chromosomes74 and later came to be associated with histone modifications75. We now have a more nuanced understanding of the molecular details, including several types of repressive histone modifications and associated proteins and the...
Percentage of genome, autosomes, X- and Y-chromosomes covered by ChIP-enriched regions for each ChIP sample, as well as percentages of the genome covered by transcriptionally active regions (TARs) (using previously published tiling array data from [32], and their definition of a TAR as “any...
interest and then isolating the antibody-bound complexes through selection for the antibody. Immunoprecipitation is a common tool in molecular biology, for more information, we point to the reader to published reviews and protocols[79–81]. After this, the crosslinks are reversed so that ...
A cell’s epigenome arises from interactions among regulatory factors—transcription factors and histone modifications—co-localized at particular genomic regions. We developed a novel statistical method, ChromNet, to infer a network of these interaction
This simple definition does not consider the degree of proximity required to be functionally meaningful nor does it speak to the length of the intervening sequence, i.e. the size of the loop. Looped structures have been detected at numerous gene loci in a fashion that juxtaposes important ...