Cioci F , Vu L , Eliason K , Oakes M , Siddiqi IN & Nomura M ( 2003 ) Silencing in yeast rDNA chromatin . Mol Cell 12 : 135 – 145 .Cioci F, Vu L, Eliason K, Oakes M, Siddiqi IN, Nomura M: Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between...
Cioci F, Vu L, Eliason K, Oakes M, Siddiqi IN, Nomura M: Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between RNA polymerase I and II. Mol Cell 2003, 12:135-145. See annotation [41].Cioci F , Vu L , Eliason K , Oakes M , Siddiqi IN & Nomura ...
SummaryAmong mammalian sirtuins, SIRT7 is the only enzyme residing in nucleoli where rDNA is transcribed. Recent reports established that SIRT7 associates with RNA Pol I machinery and is required for rDNA transcription. Although defined by its homology to the yeast histone deacetylase Sir2, current...
Accordingly, deleting rDNA repeats in Drosophila melanogaster leaves the steady-state concentration of rRNA unaltered but remodels the nucleolus and compromises heterochromatic silencing in other sites of the genome70. During fasting (Fig. 4d), mTOR inhibition (Fig. 4e) and upon RNA Pol I ...
et al. MORC family ATPases required for heterochromatin condensation and gene silencing. Science 336, 1448–1451 (2012). Article PubMed PubMed Central CAS Google Scholar Wang, C. et al. Genome-wide analysis of local chromatin packing in Arabidopsis thaliana. Genome Res. 25, 246–256 (2015...
andnuclearmyosin1(NM1),isinvolvedinregulatingrDNAtranscription,andSiRNAsilencingofWSTFleadstoareduced levelof45Spre-rRNA.ThemechanismbehindtheactionofB-WICHisunclear.Here,weshowthattheB-WICHcomplex affectsthechromatinstructureandthatsilencingoftheWSTFproteinresultsinacompactionofthechromatinstructure ...
Genome-wide mapping of yeast histone chaperone anti-silencing function 1 reveals its role in condensin binding with chromatinPLoS ONE10.1371/journal.pone.0108652 Dewari, P.S. and Bhargava, P. (2014) . 9, e108652 Google Scholar 114. Structure and function of the histone chaperone FACT - reso...
Compositions and methods are provided for treating diseases associated with aberrant silencing of gene expression such as cancer and hematological disorders by reestablishing the gene expression through inhibition of DNA hypomethylation ... JF Dimartino 被引量: 0发表: 2002年 Nucleoprotein Template: Chrom...
sub-terminally, at the distal ends of the short arms of chro- mosomes 2 and 4 (Figure 1a) (Kaul et al., 2000). In some organisms, telomeres and rDNA even show an intermin- gled arrangement. For example, in the flagellated unicellu- ...
q, Metaplot of DRIPc-seq mean coverage increase (ΔDRIPc-seq) upon BRG1-depletion over chromosomes or rDNA (n = 2). r, Venn diagram showing R-loop-forming genes in siC cells and R-loop-gain genes in siBRG1 and siUAP56 K562 cells. Other details as in Figs. 1–3. Source ...