Fig. 1.Representation of condensed heterochromatin and relaxed euchromatin. Acetylation of histones, for example, can impact chromatin accessibility and alter gene expression. Chromatin remodelingis the rearrangement ofchromatinfrom a condensed state to a transcriptionally accessible state, allowing transcription...
A. Keep the chromatin structure unchanged B. Only break down chromatin C. Alter the chromatin structure to regulate gene access D. Replace all histone proteins in the chromatin 相关知识点: 试题来源: 解析 C。解析:在植物表观遗传学中,染色质重塑复合物通过改变染色质结构来调控基因的可接近性。选项...
certain cancers can be initiated by aberrant chromatin modifications that become heritable within a population of cells. Chromatin remodeling and epigenetics are therefore areas of intense research in cancer biology, developmental biology, and neuroscience. Our reagents can help accelerate your discovery of...
To begin to understand the functions of the epigenome, we present an overview of chromatin remodeling, broadly defined to include epigenetic modifications, such as DNA methylation, histone modifications as well as the functions of chromatin remodeling complexes and noncoding RNAs. The various chromatin...
Chromatin Dynamics and Epigenetics of Stem Cells and Stem-Like Cancer Cells A.Gaspar-Maia,A.Sevilla, inChromatin Signaling and Diseases, 2016 Chromatin Remodeling Chromatin remodelingrefers to the dynamic changes of nucleosome architecture to allow access of condensed genomic DNA to the regulatory transc...
Article 23 June 2021 Targeting immune–fibroblast cell communication in heart failure Article 23 October 2024 IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling Article Open access 25 November 2023 Data...
Neuron-specific chromatin remodeling: A missing link in epigenetic mechanisms underlying synaptic plasticity, memory, and intellectual disability disordersdoi:10.1016/j.neuropharm.2013.10.002Chromatin remodelingNucleosome remodelingEpigeneticsLong-term memory...
Ramanathan R, Tuoc TC (2014) Roles of chromatin remodeling BAF complex in neural differentiation and reprogramming. Cell Tissue Res. doi:10.1007/s00441-... R Narayanan,TC Tuoc - 《Cell & Tissue Research》 被引量: 26发表: 2014年 Epigenetics and neural stem cell commitment Neural stem cell ...
Epigenetic alteration of the genome has been shown to provide palliative effects in mouse models of certain human autoimmune diseases. We have investigated whether chromatin remodeling could provide protection against autoimmune diabetes in NOD mice. Treatment of female mice during the transition from pre...
Advances in chromatin remodeling and human disease Epigenetic factors alter phenotype without changing genotype. A primary molecular mechanism underlying epigenetics is the alteration of chromatin structure... KS Cho,LI Elizondo,CF Boerkoel - 《Current Opinion in Genetics & Development》 被引量: 174...