Laskey R.A, Harland R.M, Earnshaw W.C, Dingwall C. Chromatin assembly and the co-ordination of DNA replication in the eukaryotic chromosome. In: Schweiger H, editor. International cell biology. Springer; Heidelberg: 1981. pp. 162–167....
Comparing the length of metaphase chromosomes to that of naked DNA, the packing ratio of DNA in metaphase chromosomes is approximately 10,000:1 (depending on the chromosome). This can be thought of as akin to taking a rope as long as a football field and compacting it down to less than ...
Although chromatin organizations in plants have been dissected at the scales of compartments and topologically associating domain (TAD)-like domains, there remains a gap in resolving fine-scale structures. Here, we use Micro-C-XL, a high-throughput chromosome conformation capture (Hi-C)-based techn...
必应词典为您提供Eukaryotic-chromatin-and-chromosome的释义,网络释义: 染色质与染色体;真核生物染色质和染色体;
As explained earlier, chromatin is a complex of proteins and DNA in eukaryotic cells. The nuclear DNA does not exist as linear strands but is tightly condensed and wrapped around nuclear proteins so that it can fit into the nucleus. Chromatin forms: There are two forms of chromatins in the...
1.3Eukaryoticcells SinglecellormulticellularorganismsPlantsandanimalsStructurallymorecomplex:organelles,cytoskeleton Figure1-7b 8.3GeneticandphysicalmapsoftheE.colicircularchromosome Length:About4000kb Figure8-14 NeedtopackageDNAandmakeitcompacttofitinthecell E.coliDNAisabout1mmlong.E.colicellis1µmlongand0....
nucleus. At the same time, chromatin is the substrate for functional processes such as transcription. This raises a fundamental question in chromatin biology. How is chromatin structured and packaged within a chromosome such that it can be accessed and navigated by proteins involved in DNA-based ...
2、ry,Characteristics of Eukaryotic Genome,The importance of packing of DNA into chromosomes,Chromosome is a compact form of the DNA that readily fits inside the cell To protect DNA from damage DNA in a chromosome can be transmitted efficiently to both daughter cells during cell division Chromosome...
Eukaryotic genomes are highly folded for packing into higher-order chromatin structures in the nucleus. With the emergence of state-of-the-art chromosome conformation capture methods and microscopic imaging techniques, the spatial organization of chromatin and its functional implications have been interrogat...
The eukaryotic genome is organized in the form of many long chromatin polymer chains, each essentially a string of nucleosomes—DNA wrapped around histone proteins—folded, looped, and condensed into domains of different compaction1,2,3,4. The spatial and temporal organization of these chains and...