(2012) Electric Oscillation and Coupling of Chromatin Regulate Chromosome Packaging and Transcription In Eukaryotic Cells. Theoretical Biology and Medical Modelling, 9, 27.Zhao Y, Zhan Q (2012a) Electric oscill
Comparing the length of metaphase chromosomes to that of naked DNA, the packing ratio of DNA in metaphase chromosomes is approximately 10,000:1 (depending on the chromosome). This can be thought of as akin to taking a rope as long as a football field and compacting it down to less than ...
Chromatin is a packaging material for DNA. If not packed well, it can tangle around itself or get damaged duringcell division. The size of cells is in micrometers and a DNA can be as long as 3 meters. In order to fit such a lengthy structure into a micrometer cell, tight packing is...
Physical access to DNA is a highly dynamic property of chromatin that plays an essential role in establishing and maintaining cellular identity. The organization of accessible chromatin across the genome reflects a network of permissible physical interactions through which enhancers, promoters, insulators ...
Notably, envi- ronmental changes can alter the 3D organization of the eukaryotic chromatin, as in a report in which Arabidopsis exposure to heat stress resulted in chromatin reorganiza- tion related to the activation of transposons [21]. Simi- larly, the cold treatment of rice can increase ...
To understand howinterphasechromatinis organized in eukaryotic cell nuclei, it is essential to understand what kind of interactions influence the nuclear architecture and to what extent. Using a mesoscale model that incorporates chromatin–chromatin interactions as well as binding of chromatin to thenuclea...
必应词典为您提供Eukaryotic-chromatin-and-chromosome的释义,网络释义: 染色质与染色体;真核生物染色质和染色体;
Several approximations have to be made to model the chromatin fiber as a homopolymer, i.e., a polymer with all monomers interacting in the same way, having the same size and uniform flexibility along the chain. As a first approximation, eukaryotic chromatin can be considered as a polymer fibe...
nucleus. At the same time, chromatin is the substrate for functional processes such as transcription. This raises a fundamental question in chromatin biology. How is chromatin structured and packaged within a chromosome such that it can be accessed and navigated by proteins involved in DNA-based ...
Genomes of many eukaryotic species have a defined three-dimensional architecture critical for cellular processes. They are partitioned into topologically associated domains (TADs), defined as regions of high chromatin inter-connectivity. While TADs are not a prominent feature of A. thaliana genome organ...