The loop size in derivatives isolated using the most 'physiological' conditions was 86 kb; this remained unchanged throughout the cell cycle. This loop size is probably an average of a range of loops of between 5 and 200 kb. 展开 关键词:...
Chromatin assembly in a yeast whole-cell extract. Focuses on a study which found that DNA ligase I plays a significant role in template repair during assembly in a yeast whole-cell extract. Development of ... Schultz,Michael,C.,... - 《Proceedings of the National Academy of Sciences of th...
Chromatin changes in cell transformation: progressive unfolding of the higher-order structure during the evolution of rat hepatocyte nodules. A differentia... Using differential scanning calorimetry and complementary ultrastructural observations, we have characterized the status of chromatin during the transform...
Chromatin of mammalian nucleus folds into discrete contact enriched regions such as Topologically Associating Domains (TADs). Folding hierarchy and internal organization of TADs is highly dynamic throughout cellular differentiation, and are correlated wi
We validated Chem-map for the BET inhibitor JQ1 in human leukemia K562 cells, as JQ1 interactions have been characterized using Click-Chem-seq in the same cell line5. In parallel, we mapped the genome-wide binding sites of the inhibitor’s main target BRD4 using a specific antibody and the...
Chromosome condensation induced by geminivirus infection of mature plant cells Tomato golden mosaic virus (TGMV) is a geminivirus that replicates its single-stranded DNA genome through double-stranded DIVA intermediates in nuclei of d... Bass,HW,Nagar,... - 《Journal of Cell Science》 被引量: ...
A large-scale application of the “stacked modeling” approach for chromatin state discovery previously provides a single “universal” chromatin state annotation of the human genome based jointly on data from many cell and tissue types. Here, we produce an analogous chromatin state annotation for mo...
a system and to quantitate the interactions using quantitative polymerase chain reaction (qPCR). Chromatin IP experiments require a variety of proteomics and molecular biology methods including crosslinking, cell lysis (protein–DNA extractio...
Studies the interaction of Xenopus laevis sperm and eggs. Extracellular layer overlaying the egg plasma membrane in the eggs of animal species; Important r... Tian,Jingdong,Gong,... - 《Journal of Cell Biology》 被引量: 101发表: 1997年 Egg jelly influences sperm motility in the externally ...
继续接上面一篇文章,题目是:A human cell atlas of fetal chromatin accessibility,同期的一篇back to back, 80Wde fetal human cell 进行了chromatin accessibility的表征。 A human cell atlas of fetal chromatin accessibility enables the exploration of in vivo gene regulation across diverse cell types 思路其实...