Higher plasma levels of 24-OHC were associated with age, gender, the presence of high grade white matter hyperintensities, and brain infarcts on prior MRI. Participants with higher plasma 24-OHC and a greater ratio of 24-OHC/27-OHC were also more likely to develop incident cognitive impairment...
In a relatively large series, 100 patients underwent surgery (over 12 years) for the cholesterol crystal embolization syndrome.38 The embolic source was located by a combination of CT scanning, angiography, ultrasound, transesophageal echocardiography, and MRI. Occlusive aortoiliac disease or small ...
Resultantly, 3,144 health check-up participants were included in the final analyses. Korean medical services are characterized by high accessibility to brain imaging and relatively reasonable medical costs. Because of this, many people perform brain MRI for health screening purposes even without suspect...
The brain has less abundant and much smaller peroxisomes than the liver and kidney, with the exact distribution of peroxisomes depending on the detection methods and developmental stages [2]. At the cellular level, peroxisomes are found in both neurons and glial cells including astrocytes, ...
Cholesterol (Chol) fortifies packing and reduces fluidity and permeability of the lipid bilayer in vesicles (liposomes)-mediated drug delivery. However, under the physiological environment, Chol is rapidly extracted from the lipid bilayer by biomembranes, which jeopardizes membrane stability and results ...
42 It also is an important aspect of second messenger systems in the brain and is essential for neurotransmission.42 Elevated cholesterol levels may be a marker of poor nutrition or vascular disease, either of which may be associated with poor response to antidepressants. In addition, cholesterol ...
In the adult brain, neurons require local cholesterol production, which is supplied by astrocytes through apoE-containing lipoproteins. In Huntington’s disease (HD), such cholesterol biosynthesis in the brain is severely reduced. Here we show that this
3) brain development 脑发育 1. Neurological assessment of brain development and brain function of preterm infants; 早产儿脑发育及脑功能的评价 2. Effects of enriched environmental stimulation on brain development in cerebral palsy rats; 早期丰富环境刺激对脑瘫大鼠脑发育的影响 3. The changes of ...
Hajnal JV, Bryant DJ, Kasuboski L, Pattany PM, De Coene B, Lewis PD et al (1992) Use of fluid attenuated inversion recovery (FLAIR) pulse sequences in MRI of the brain. J Comput Assist Tomo 16(6):841–844CrossRef Havel RJ (2000) Genetic underpinnings of LDL size and density: a...
Dbait molecule distribution was assessed in the whole organ with 2D-FRI and in brain sections. CoDbait was chosen for further studies given its good retention in the brain, cellular localization, and efficacy in inducing the activation of DNA repair effectors. The radiosensitizing effect of coD...