Cholesterol metabolism and homeostasis in the brain. Protein Cell 6, 254-264.Zhang J, Liu Q. Cholesterol metabolism and homeostasis in the brain. Protein Cell. 2015;6(4):254-264. DOI: 10.1007/s13238‐014‐0131‐3J. Zhang and Q. Liu, "Cholesterol metabolism and homeostasis in the brain,...
Our results suggest that altered cholesterol metabolism in the brain has implications for synaptic plasticity as well as learning and memory.doi:10.1096/fasebj.20.4.A85Denise O'Donnell RamirezDepartment of Molecular GeneticsUniversity of Texas Southwestern Medical Center5323 Harry Hines Blvd.DallasTX75390...
Here, researchers describe an advanced mass spectrometry imaging platform to reveal spatial cholesterol metabolism in mouse brain at micrometre resolution from tissue slices. The researchers mapped not only cholesterol, but also biologically active metabolites arising from cholesterol turnover. For example, ...
However, the molecular mechanisms underlying the correlation between altered cholesterol metabolism and the neurological deficits are, for the most part, not clear. NPC disease and SLOS are caused by mutations in genes involved in the biosynthesis or intracellular trafficking of cholesterol...
Dietschy JM, Turley SD. Cholesterol metabolism in the brain. Current opinion in lipidology. 2001 Apr 1;12(2):105-12. Akk G, Bracamontes JR, Covey DF, Evers A, Dao T, Steinbach JH. Neuroactive steroids have multiple actions to potentiate GABAA receptors. The Journal...
Cholesterol metabolism deficiency. 来自 学术范 喜欢 0 阅读量: 27 作者:Jira,Petr 摘要: Genetic defects in enzymes responsible for cholesterol biosynthesis have emerged as important causes of congenital dysmorphology and retardation syndromes. Cholesterol is an important constituent of the cell membrane of...
P.6.c.012 - Impact of repeated administration of cocaine on the expression of genes involved in cholesterol metabolism in the rat braindoi:10.1016/S0924-977X(17)31854-0J.AlsebaalyL.RabbaaKhabbazE.DugastM.SolinasN.SDOSEuropean Neuropsychopharmacology...
Lipoprotein metabolism in pregnancy, fat transport to the fetus, and the effects of diabetes. Preliminary studies suggest that it depends on HDL as well as LDL since both can provide cholesterol for placental progesterone synthesis. In addition, ... RH Knopp,MR Warth,D Charles,... - 《...
The strange idea that cholesterol causes atherosclerosis was revived in the 1950s when the vegetable oil industry learned that their polyunsaturated oils lowered serum cholesterol. (Many other toxins lower cholesterol, but that is never mentioned.) The industry began advertising their oils as "heart ...
transport (RCT), the pathophysiological effect of hypercholesterolemia, and therapeutic strategies to counteract hypercholesterolemia and its associated CVD.The liver plays a central role in whole-body cholesterol homeostasis, thus perturbations in hepatic cholesterol metabolism can result in hypercholesterolemia...