For cell-based studies, we grew both neurons and fibroblast cells on large-area monolayer graphene sheets. In neurons on graphene, we find increased cell membrane cholesterol and significant increases in the number, the release probability, and the turnover rate of synaptic vesicles—all of which...
2 Role of cholesterol at the plasma membrane: Biophysical properties and protein function Sterols are important structural components of cell membranes. In the animal kingdom, cholesterol is by far the most abundant sterol, representing on average, over one third (mol/mol) of the total lipids in...
It has been shown that disruption of cellular homeostasis caused by leaky cell membrane leads to cell apoptosis via the caspase signaling pathway95,96,97. Applying dead cell apoptosis kit, we treated the HepG2 cells withCh-C1at 16 µM for 24 h, stained the cells using both green An...
cholesterol contributes to the decreased fluidity of the cell membrane as the molecule is in a trans conformation making all but the side chain of cholesterol rigid and planar. In this structural role, cholesterol reduces the permeability of the plasma membrane to neutral solutes, protons, and ...
产品名称:细胞膜修饰胆固醇的脱氧核糖核酸 英文名称:Cell membrane-cholesterol-DNA 产地:西安 规格:1mg 5mg 10mg 纯度:99% 用途:仅用于科研 温馨提示:仅用于科研,不能用于人体实验!DNA一般指脱氧核糖核酸。 脱氧核糖核酸(英文DeoxyriboNucleic Acid,缩写为DNA)是生物细胞内含有的四种生物大分子之一核酸的一种...
Cell membranes have a nonhomogenous lateral organization. Most information about such nonhomogenous mixing has been obtained from model membrane studies wh... TKM Nyholm,D Lindroos,B Westerlund,... - 《Langmuir》 被引量: 58发表: 2011年 Analyte test system for determining the concentration of an...
Cell Biol., 1 (2000), pp. 31-39 View in ScopusGoogle Scholar [5] D.A. Brown, E. London Structure and function of sphingolipid- and cholesterol-rich membrane rafts J. Biol. Chem., 275 (2000), pp. 17221-17224 View PDFView articleView in ScopusGoogle Scholar [6] W.I. Lencer, D....
Cell to cell cohesion in fully keratinized hair is mediated by a cell membrane complex which contains covalently bound (integral) hair lipids. The influence of aging on concentrations of integral cholesterol sulphate (CHSU) and cholesterol (CH) in human scalp hair shafts, and the relationship bet...
In addition, membrane cholesterol significantly modulates the stability, ligand-binding properties and function of several GPCRs (reviewed in refs 3, 4, 5, 6). Specifically, the presence of cholesterol in cell membranes can either enhance7,8,9,10,11 (that is, positively modulate) or decrease...
cell membrane is approximately one order of magnitude less permeable to cisplatin in comparison to the membrane of the normal cell. We discuss possible reasons for this difference in details and compare obtained results with available experimental data. We use the ISD methodology to compare ...