A method to track changes in the amount of cholesterol in a single cell's plasma membrane has been developed by chemists at case western reserve university the amount and distribution of cholesterol-a sterol lipid that regulates membrane fluidity and permeability-in the plasma membrane influences ...
产品简介：Cyanine3-Cholesterol，是荧光染料与胆固醇的完美结合，展现了强大的组织穿透力和超低的细胞毒性。Cyanine3-Cholesterol是一种荧光染料与胆固醇的结合物。这种试剂具有良好的组织穿透力和低细胞毒性。Cyanine3-Cholesterol是一种具有良好灵敏的试剂，能够检测胆固醇在细胞膜中的分布情况，因此可以用于研究胆固醇代谢、...
The ability of these five molecules (Ch-Pns andCh-C1) to self-assemble into a membrane-active ion-transporting pore in the presence of cholesterol (Ch) molecules was assessed using the well-established pH-sensitive fluorescence assay (Fig.2a), employing large unilamellar vesicles (LUVs) containin...
Membrane LipidsPhospholipidsSphingolipidsRecent studies concerning cholesterol, its behavior and its roles in cell growth provide important new clues to the role of this fascinating molecule in normal and pathological states.doi:10.1016/0304-4157(85)90011-5Philip L. Yeagle...
Cholesterol forms lipid rafts in specific regions with sphingolipids in cell membrane. Lipid rafts regulates signaling molecule assembly, membrane fluidity, protein trafficking in cell transformation and cancer progression.85–87A recent study showed that cholesterol inhibits HCC invasion and metastasis by ...
It co-localizes with dehydroergosterol, a marker of cholesterol, in HeLa cells and is trafficked from the plasma membrane to the endocytic recycling compartment in BHK cells. 2 它与胆固醇标记物脱氢麦角甾醇在HeLa细胞中共定位,并从BHK细胞质膜运输到的内吞循环室。2 ...
Of note, the phospholipids present in the cell membrane contain a double aliphatic chain29. To further improve the therapeutic delivery efficiency of Lipo and better mimic the cell membrane composition, we proposed to engineer an improved lipid bilayer through covalently conjugating sphingomyelin (SM...
Cholesterol is essential to life; it is a primary component of the membrane that surrounds each cell, and it is the starting material or an intermediate compound from which the body synthesizes bile acids, steroid hormones, and vitamin D. Cholesterol circulates in the bloodstream and is ...
membrane (PM) ofCaenorhabditis elegansspermatids but is translocated to and subsequently enters the invaginated membrane of the spermatozoa cell body during sperm activation. The polarization of NKA depends on the transport of cholesterol from the PM to membranous organelles (MOs) via membrane contact...
L. et al. Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 124, 1209–1223 (2006). Article CAS PubMed Google Scholar Matyash, V. et al. Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive ...