Horizon Discovery CHO工程细胞系来源于ECACC(欧洲细胞库) CHO-K1 细胞,应用Horizon Discovery的重组腺病毒(rAAV)技术,通过同源重组的方式将GS基因(谷氨酰胺合成酶)第六外显子(酶催化活力必须元件)敲除,得到无谷氨酰胺合成酶的CHO-K1细胞系,进一步驯化为悬浮细胞,适应现有商业化学限定的无动物源性的培养基,从而得到...
该研发生产平台正是使用了Horizon CHO-GS敲除细胞体系! 2019年9月,Batavia宣布了Horizon CHO-GS cell line 商业许可证用于表达生产,CHOSOURCE™. 采用该细胞系统的完整服务,包括细胞系生成、过程开发及批量生产,由Batavia作为STEP®-mAb进行销售。CHO-GS敲除表达系统是实现产品高产量的行业标准。此外,它能在稳定...
三优生物拥有完整的创新抗体药物研发实验室,CHOSOURCE能够脱颖而出,为他们的生物治疗方法开发以及一体化解决方案提供帮助也是我们喜闻乐见的事情。”Horizon生物生产事业部全球负责人Jesús Zurdo表示,“Horizon致力于使用我们的表达平台,为...
泰诺麦博解释道:“自从2019年3月在我们的药物开发工作流程中部署CHOSOURCE CHO-K1基因敲除细胞系以来,我们已能开创先河,去开发这款针对不同疾病的mAb候选药物,包括在澳大利亚开展首项针对破伤风毒素的人类单抗I期试验。上述努力显示,部署Horizon细胞系并使其适应我们的流程是如此轻松和有效。我们对上述结果感到满意,会继...
April 2025 verschoben.„Horizon 2“ von und mit Kevin Costner startet in Deutschland am 3. April 2025 (Credit: Biennale di Venezia)„Horizon 2“ (hier unsere Spot-Besprechung) hatte auf der Mostra in Venedig seine Weltpremiere gefeiert und sollte am 7. November in die deutschen Kinos...
(以下简称ExpiCHO SPM) 稳定生产型培养基沿用Gibco AGT 专利技术,它是一种无蛋白质、无水解物、无生长因子、无任何动物来源成分的一款化学成分限定的培养基, ExpiCHO SPM支持从瞬转到稳转的简单过渡,提供细胞高表达量而不需要额外的培养基优化,既可以作为单克隆培养基,提高单克隆的形成率,也适应于所有CHO细胞的大...
enabling access to the CHOSOURCE platform in such a way as to empower organizations of all sizes to drive efficiencies in development and production of biotherapeutics,” added Terry Pizzie, CEO of Horizon Discovery
and thinks they're going to get there. I would probably take a much more cautious approach, saying that it's possible we might, if we all agree on what it is, but I think that that's what a lot of our newer therapies and targets are really trying to go after,” Chovatiya told ...
The CHOSOURCE™ expression platform provides an enhanced system for the development and manufacturing of biotherapeutics compatible with existing processes that can be used in commercial manufacturing applications. Helping you streamline cell line development, improve productivity, and accelerate biotherapeutic...
GTNewHorizons / NewHorizonsCoreMod Public Notifications Fork 152 Star 65 Code Pull requests 4 Actions Wiki Security Insights New issue fix small bop to gt color bug #1073 Merged Dream-Master merged 1 commit into GTNewHorizons:master from chochem:small-bop-color-fix Nov 7, 2024 ...