The chlorpromazine cue generalized to the atypical antipsychotics clozapine (ED50 for the clozapine curve was 0.258 mg/kg [95% CI = 0.047–1.420 mg/kg]) and olanzapine (ED50 for the olanzapine curve was 0.199 mg/kg [95% CI = 0.076–0.522 mg/kg]) and to the typical antipsychotic ...
We reliably selected all randomised clinical trials comparing penfluridol to placebo or typical or atypical antipsychotic drugs for schizophrenia or serious mental... S Leucht,B Hartung - 《Cochrane Database Syst Rev》 被引量: 36发表: 2002年 Chlorpromazine versus reserpine for schizophrenia In the 19...
Chlorpromazine can help to manage your condition, but it will not cure it, so it is important to take your medication exactly as prescribed by your doctor. Taking more or less than you are prescribed, or regularly missing doses, can lead to an increase in symptoms and a worsening of your...
Chlorpromazine is a member of the typical antipsychotic or neuroleptic drug class, also known as first-generation antipsychotics (FGAs). Its precise mechanism of action is unknown, but it is believed to produce its antipsychotic effect by the post-synaptic blockade at the D2 receptors in the meso...
Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-...
or are selective for D4 receptorsNeuropsychopharmacology16(2)93-110(1997) 3.Kroeze, W.K., Hufeisen, S.J., Popadak, B.A., et al.H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugsNeuropsychopharmacology28(3)519-526(2003) 4.Terry, A....
Analyses of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week ...
Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine ver... olanzapinequetiapinerisperidonesertindoleziprasidonehaloperidolchlorpromazineantipsychoticthree-choice drug discriminationThe prototypical atypical antipsychotic...
Prevalence of hyperprolactinemia in schizophrenia: Association with typical and atypical antipsychotic treatment OBJECTIVE: To evaluate the prevalence and severity of hyperprolactinemia among a large sample of patients with schizophrenia and related psychotic disorder... J Montgomery,E Winterbottom,M Jessani,...
(a typical motor region of the basal ganglia) -' modification of prolactin secretion results from blockade of d 2 receptors in' the anterior pituitary. however, this hypothesis cannot satisfactorily account for the pharmacological profiles of atypical antipsychotics and the debate concerning their ...