The mode of action of the inhibitory effect of CPZ on 13,14-dihydroprostaglandin F2-alpha (13, 14H 2-PGF2-alpha) formation in rat ovary was examined. The inhibition of 13, 14H 2-PGF2-alpha formation and of ovulation induced by a proestrus were completely recovered by an injection of ...
The mode of action of chlorpromazine on mitochondrial membrane permeability to K+. 1. 1. The effects of chlorpromazine on parameters related to potassium transport in isolated rat liver intact mitochondria were investigated. 2. 2. The results showed that chlorpromazine induced the passive permeability...
(1955), NARCOBIOTIC ACTIVITY AND THE MODE OF ACTION OF CHLORPROMAZINE. Anaesthesia, 10: 221–232. doi: 10.1111/j.1365-2044.1955.tb01607.x Author Information PARIS † Translated and revised by D. A. Buxton Hopkin. Publication History Issue published online: 22 FEB 2007 Article first ...
Chlorpromazine A familiar brand name for the antipsychotic drug chlorpromazine (CPZ) is Thorazine and Largactil. It is mostly used to treat psychotic disorders such as schizophrenia. Other uses include the management of bipolar disorder, severe behavioral problems in children, including those brought o...
The common mode of action of the first-generation antipsychotics is believed to be blockade of the D2 subtype ofdopamine receptors(Pickar1995). Blockade of these receptors in the mesolimbic dopamine system is thought to cause a reduction in positive symptoms, and blockade in the nigrostriatal dopam...
However, protein is not associated with the broken DNA after chlorpromazine treatment suggesting a different mode of action on the topoisomerase. Reasons why chlorpromazine may have potential as an anti-cancer agent are considered. 展开 关键词:...
1. The effects of chlorpromazine and imipramine on the human nocturnal sleep EEG were investigated and the difference in the mode of action of drugs was observed. 2. Administration of chlorpromazine did not markedly modify the EEG activi... Toyoda,Junzo - 《Psychiatry & Clinical Neurosciences》 ...
Effects of mode of management on plasma chlorpromazine in psychiatric patients. Clin Pharmacol Ther 1973; 14: 978–86. 3. Loga S, et al. Interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man. Br J Clin Pharmacol 1975; 2: 197–208. ...
417-22. 2. rivera-calimlim l, et al. effects of mode of management on plasma chlorpromazine in psychiatric patients. clin pharmacal ther 1973; 14: 978-86. 3. loga s, et al. interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man. br j ...
Haloperidol enhancement of LI was unaffected by the coadministration of the anticholinergic agent trihexyphenidyl. Enhancement of LI is exhibited by the ... LA Dunn,GE Atwater,CD Kilts - 《Psychopharmacology》 被引量: 273发表: 1993年 Effects of mode of management on plasma chlorpromazine in psychia...