Chitin synthesis in human pathogenic fungiS. cerevisiae A. nidulans C. albicans A. fumigatusC. A. MUNRON. A. R. GOW
Chapter 8Chitin Synthesis and Degradationin Fungi: Biology and EnzymesJinkui Yang and Ke-Qin ZhangAbstract Chitin is one of the most important carbohydrates of the fungal cell wall,and is synthesized by chitin synthases. Chitin can be degraded by chitinases, whichare important virulence factors in...
The cellular basis of chitin synthesis in fungi and insects: Common principles and differences 2011, European Journal of Cell Biology Show abstract The fungal cell wall: Structure, biosynthesis, and function 2017, Microbiology Spectrum Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated ...
The prevalence of chitin and chitosan in the mechanically crucial core ofR. delemarcell walls prompted us to evaluate the impact of chitin inhibitors on this fungus. We applied nikkomycin Z (Fig.4a), the only UDP-GlcNAc analog known to block chitin synthesis in fungi51,52, toR. delemarcult...
In fungi, after their synthesis, the Chs are packaged into microvesicles with a diameter of approximately 60 nm, called chitosomes (Leal-Morales et al., 1988). These chitosomes bring the Chs to the hyphal tip of the cell membrane. Recently, it was demonstrated that all the seven Chs from...
Unfortunately there are only a limited number of antimycotic drugs in use. Promising targets for drugs specific against fungi are those affecting chitin synthesis. Chitin is absent in vertebrates, and is essential for fungal wall integrity. A thorough knowledge of the mechanism of chitin synthesis ...
The Antifungal Protein AFP from Aspergillus giganteus Inhibits Chitin Synthesis in Sensitive Fungiᰔ The Antifungal Protein AFP from Aspergillus giganteus Inhibits Chitin Synthesis in Sensitive FungiᰔFIG. 1. Alignment of amino acid sequences of AFP and ... S Hagen,F Marx,AF Ram,... 被引量:...
Many fungi are rich in chitin and chitosan in their cell walls, which makes fungi become a new and potential source of chitin and chitosan. The existences of chitin and chitosan in fungi, methods of preparing, as well as some problems of obtaining chitin and chitosan from fungi were reviewed...
The cellular basis of chitin synthesis in fungi and insects: Common principles and differences. Eur. J. Cell Biol. 2011, 90, 759–769. [Google Scholar] [CrossRef] [PubMed] Dermauw, W.; Van Leeuwen, T. The ABC gene family in arthropods: Comparative genomics and role in insecticide ...
Multiple gene products have been implicated in the regulation and localization of chitin synthesis in S. cerevisiae, but describing them is beyond the scope of this chapter; useful reviews of chitin synthesis include those of Munro and Gow (2001) and Roncero (2002). Most fungi have multiple ...