It’s hard to say which specific combination of chemo and other drugs would work best for certain groups of people, like younger vs. older people. Each type of multiple myeloma drug isn’t necessarily limited to one group or another, says Krina K. Patel, MD, of MD Anderson Cancer Center...
Other drugs, such as erythropoietin, interferon gamma or all-trans-retinoic acid deserve further evaluation.doi:info:doi/10.1016/S0248-8663(99)80112-XFacon TLa Revue De Médecine Interne
Antibody-drug conjugates (ADCs), cytotoxic drugs chemically linked to antibodies, provide a means to increase the effectiveness of chemotherapy by targetin... AG Polson,MX Sliwkowski - 《Clinical Cancer Research》 被引量: 18发表: 2009年 Combination chemotherapy for multiple myeloma with BCNU, cycl...
An update on drug combinations for treatment of myeloma. Multiple myeloma is the second most common haematological malignancy. It is becoming increasingly manageable with conventional and high-dose chemotherapy b... M Srikanth,FE Davies,GJ Morgan - 《Expert Opinion on Investigational Drugs》 被引量:...
Based on the possible shared mechanisms of chemotherapy-induced peripheral neuropathy (CIPN) for different drugs, we aimed to aggregate results of all previously published genome-wide association studies (GWAS) on CIPN, and to replicate them within a cohort of multiple myeloma (MM) patients. Followi...
To make this possible, only bactericidal drugs were included as components; 3. Rifampicin (RMP) was included as a key component because of its powerful bactericidal effect against M. leprae. It was to be administered only once monthly under supervision, both to insure compliance and because of ...
A new standard combination for recurrent ovarian cancer? Ovarian cancer that recurs more than 6 months following primary chemotherapy can respond to many different drugs, but retreatment with a combination of carboplatin and paclitaxel has become a standard of care. A combination of pegylated liposomal...
Some drugs damage the DNA of cancer cells to keep them from making more copies of themselves. They are called alkylating agents, the oldest type of chemotherapy. They treat many different types of cancer, such asleukemia,lymphoma,Hodgkin's disease,multiple myeloma, andsarcoma, as well as breast...
Chemotherapy is the major treatment option for many cancers in combination with surgery. Many different mechanisms of action can be used as anti-cancer therapy. Some drugs are anti-proliferative or target rapidly dividing malignant cells, while others inhibit angiogenesis or induce apoptosis. Anti-canc...
After 29 months, 136 patients in the ADT-only group died compared with 101 men in the group who received both drugs. The median overall survival was 57.6 months for patients receiving early chemotherapy compared with 44 months in the group where ADT was the only initial treatme...