Chemokines and chemokine receptors(趋化因子及受体) 简介 趋化因子(Chemokines)或称趋化细胞因子,是由细胞分泌的一系列小细胞因子或信号蛋白,可诱导白细胞以及包括内皮细胞和上皮细胞在内的其他类型细胞定向移动。除了在激活宿主免疫反应中发挥重要作用外,趋化因子对生物过程(包括形态形成和伤口愈合)以及癌症等疾病的...
网络趋化因子及其受体 网络释义 1. 趋化因子及其受体 趋化因子及其受体(Chemokines and chemokine receptors)可在免疫反应及炎症过程中发挥重要作用。研究发现,趋化因子CCL2 … cdmd.cnki.com.cn|基于 1 个网页
Miller MD, Krangel MS (1992) Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol 12: 17–46 PubMed CAS Google Scholar Sozzani S, Locati M, Zhou D et al. (1995) Receptors, signal transduction and spectrum of action of monocyte ...
We will also discuss chemokine receptors, their cellular expression, and their intracellular signaling mechanisms. The role of chemokines in cell trafficking will be reviewed in terms of their role in homeostasis and development and their participation in cell recruitment to sites of inflammation. ...
Chemokines, a complex superfamily of small, secreted proteins, were initially recognized for their chemotactic effects on various immune cells. Chemokines constitute both physiological and inflammatory cell positioning systems and mediate cell localization to certain sites via interaction with their receptors,...
Over the last decade, a family of chemotactic cytokines called chemokines, have been found to be involved in the trafficking of leukocytes in both the normal and pathological states. The expression of these chemokines and their receptors is increased during the acute phase of MS and also in the...
Chemokines and Chemokine Receptors Manel Juan, Servei d'Immunologia, Hospital Cl´ınic (CDB), Institut d'Investigacions Biome`diques August Pi i Sunyer, Barcelona, Catalonia, Spain Roger Colobran, Laboratori d'Immunobiologia per a la Recerca i Aplicacions Diagno` stiques (LIRAD), Banc de ...
The CC receptors bind to the CC chemokines and are named CCR1 to 9; the CXC chemokines selectively bind to the CXC receptors, termed CXCR1 to CXCR5. This group also comprises receptors for fractalkine (CX3CR1) and lymphotactin (XCR1), as well as the Duffy antigen receptor for chemokines...
nature publishing group Chemokines / Chemokine Receptors Monday, July 6 M.42. Regulation of Intestinal Dendritic Cells and Immunity by the CCX-CKR Decoy Receptor for CCL19, 21 and 25 Elinor Anderson, Iain McInnes, Robert Nibbs, Allan Mowat Glasgow University, Glasgow, United Kingdom Lymphocyte...